Results 251 to 260 of about 42,851 (291)
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Current Opinion in Plant Biology, 2001
Glycosyltransferases are involved in the biosyntheses of cell-wall polysaccharides, the addition of N-linked glycans to glycoproteins, and the attachment of sugar moieties to various small molecules such as hormones and flavonoids. In the past two years, substantial progress has been made in the identification and cloning of genes that encode ...
K, Keegstra, N, Raikhel
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Glycosyltransferases are involved in the biosyntheses of cell-wall polysaccharides, the addition of N-linked glycans to glycoproteins, and the attachment of sugar moieties to various small molecules such as hormones and flavonoids. In the past two years, substantial progress has been made in the identification and cloning of genes that encode ...
K, Keegstra, N, Raikhel
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Antibiotic glycosyltransferases
Biochemical Society Transactions, 2003In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycosyltransferases in the latter stages of the pathways. Two glycosylation pathways will be examined: the glycopeptide antibiotics of the vancomycin class and the aminocoumarin antibiotics of the novobiocin class.
C T, Walsh +2 more
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Glycoconjugate glycosyltransferases
Glycoconjugate Journal, 2008Assay methods for representative glycosyltransferases were described, covering those involved in the synthesis of glycosphingolipids, N-glycans, O-glycans, and proteoglycan glycosaminoglycans. In addition, intracellular localization of glycosyltransferase was comprehensively summarized.
Koichi, Furukawa +3 more
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Iminosugars as glycosyltransferase inhibitors
Organic & Biomolecular Chemistry, 2021The review describes the syntheses and inhibition properties of pyrrolidine, piperidine, azepane, pyrrolizidine and indolizidine iminosugars, as well as iminosugar nucleotides and iminodi- and -oligosaccharides.
Irene Conforti, Alberto Marra
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GLYCOSYLTRANSFERASES IN OLIGOSACCHARIDE SYNTHESIS
Journal of Carbohydrate Chemistry, 2001AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiangping Qiam +3 more
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Glycosyltransferases as biocatalysts
Current Opinion in Chemical Biology, 2011Glycosyltransferases are useful synthetic tools for the preparation of natural oligosaccharides, glycoconjugates and their analogues. High expression levels of recombinant enzymes have allowed their use in multi-step reactions, on mg to multi-gram scales.
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Glycosyltransferase structure and mechanism
Current Opinion in Structural Biology, 2000The high-resolution X-ray crystal structures of a new form of bacteriophage T4 beta-glucosyltransferase, Escherichia coli MurG, Bacillus subtilis SpsA, bovine beta-1,4-galactosyltransferase 1 and rabbit N-acetylglucosaminyltransferase I have now been solved.
U M, Unligil, J M, Rini
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2015
AbstractThe stereo- and regioselective properties and the high selectivity of glycosyltransferases toward donor and acceptor substrates make these enzymes highly attractive for synthetic applications. Various examples of recombinantly expressed glycosyltransferases demonstrate the versatility of both in vivo and in vitro syntheses of oligosaccharides ...
J. Voglmeir, S. L. Flitsch
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AbstractThe stereo- and regioselective properties and the high selectivity of glycosyltransferases toward donor and acceptor substrates make these enzymes highly attractive for synthetic applications. Various examples of recombinantly expressed glycosyltransferases demonstrate the versatility of both in vivo and in vitro syntheses of oligosaccharides ...
J. Voglmeir, S. L. Flitsch
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Exploring genomes for glycosyltransferases
Molecular BioSystems, 2010Glycosyltransferases are one of the largest and most diverse enzyme groups in Nature. They catalyse the synthesis of glycosidic linkages by the transfer of a sugar residue from a donor to an acceptor substrate. These enzymes have been classified into families on the basis of amino acid sequence similarity that are kept updated in the Carbohydrate ...
Fasmer Hansen, Sara +4 more
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