Results 131 to 140 of about 602 (161)

Carbohydrate-binding module assisting glycosynthase-catalysed polymerizations

Biochemical Journal, 2015
Carbohydrate-binding modules (CBMs) are found within multi-modular polysaccharide degrading enzymes [glycoside hydrolases (GHs)]. CBMs play a critical role in the recognition of plant cell-wall polysaccharides and enhance the hydrolase activity of their cognate catalytic domains by increasing enzyme substrate proximity.
Codera V, Gilbert HJ, Faijes M, Planas A
openaire   +3 more sources

Expansion of the glycosynthase repertoire to produce defined manno-oligosaccharides

Chem. Commun., 2003
Mutant endo-mannanases, in which the catalytic nucleophile has been replaced, function as glycosynthases in the synthesis of manno-oligosaccharides of defined lengths.
Jahn M, Stoll D, Warren RAJ, Szabo L, Singh P, Gilbert HJ, Ducros VM-A, Davies GJ, Withers SG   +8 more
openaire   +3 more sources

Glycosynthases as tools for the production of glycan analogs of natural products

Natural Product Reports, 2012
Oligo-, polysaccharides, and glycoconjugates are a relevant part of the bioactive components of the natural products exploited in therapeutics, diagnostics, food additives, and biomaterials. Glycans are directly involved in important biological processes, such as immunostimulation, anti-inflammatory, antioxidant, and chemoprotectant actions and/or are ...
CobucciPonzano Beatrice, Moracci Marco
openaire   +5 more sources

Unexpected regioselectivity of Humicola insolens Cel7B glycosynthase mutants

Carbohydrate Research, 2007
Four Humicola insolens Cel7B glycoside hydrolase mutants have been evaluated for the coupling of lactosyl fluoride on O-allyl N(I)-acetyl-2(II)-azido-beta-chitobioside. Double mutants Cel7B E197A H209A and Cel7B E197A H209G preferentially catalyze the formation of a beta-(1-->4) linkage between the two disaccharides, while single mutant Cel7B E197A and
Blanchard, S., Armand, S., Couthino, P., Patkar, S., Vind, J., Samain, E., Driguez, H., Cottaz, S.   +7 more
openaire   +2 more sources

Auxiliary Active Site Mutations Enhance the Glycosynthase Activity of a GH18 Chitinase for Polymerization of Chitooligosaccharides

Carbohydrate Polymers, 2021
Antoni Planas, Almudena Aranda-Martinez, Enea Sancho-Vaello   +2 more
exaly  

Size-Controlled Synthesis of β(1→4)-GlcNAc Oligosaccharides Using an Endo-Glycosynthase

Chemistry - A European Journal, 2021
Sylvain Cottaz, Sébastien Fort, Antoine Rousseau   +2 more
exaly  

NOVEL GLYCOSYNTHASE

2023
GRUNDLING IRIA, DENNIG ALEXANDER, NACHSCHATT MATTHIAS, ZHYLITSKAYA HALINA, OSZTROVSZKY GYÖRGYI, HORVATH FERENC   +5 more
openaire   +1 more source

1,2-α-L-Fucosynthase: A Glycosynthase Derived From an Inverting α-Glycosidase With an Unusual Reaction Mechanism

FEBS Letters, 2008
Motomitsu Kitaoka, Kenji Yamamoto, Ryuichi Kato   +2 more
exaly  

Rice BGlu1 Glycosynthase and Wild Type Transglycosylation Activities Distinguished by Cyclophellitol Inhibition

Carbohydrate Research, 2012
Salila Pengthaisong, Stephen Withers, James Ketudat Cairns   +2 more
exaly  

A Transitional Hydrolase to Glycosynthase Mutant by Glu to Asp Substitution at the Catalytic Nucleophile in a Retaining Glycosidase

Carbohydrate Research, 2014
Antoni Planas, Estela Castilla, Xevi Biarnés   +2 more
exaly