Results 101 to 110 of about 6,171 (143)

Antileukæmic Activity of Glycyrrhetinic Acid

Nature, 1960
RECENTLY some pharmacologically interesting activities of glycyrrhetinic acid corresponding to those observed with the adrenal cortical hormones have been shown; for example, a DOCA-like effect on sodium and potassium metabolism in normal people1 and an anti-inflammatory activity in different animal tests2.
W, LOGEMANN   +3 more
openaire   +2 more sources

Metabolism of Glycyrrhetinic Acid in Human Subjects

Nature, 1954
IN a series of publications Groen, Pelser, Frenkel, Kamminga and Willebrands1–6 have reported on the successful treatment of Addison's disease by extract of liquorice, glycyrrhizinic acid or glycyrrhetinic acid. It was shown that either the crude liquorice extract or its active component produced an effect on electrolyte metabolism which was entirely ...
V M, VAN KATWIJK, L G, HUIS IN'T VELD
openaire   +2 more sources

Interaction of Glycyrrhizin and Glycyrrhetinic Acid with DNA

DNA and Cell Biology, 2012
Glycyrrhizin (GL), a molecule of glycyrrhetinic acid (GA), is an aqueous extract from licorice root. These compounds are well known for their anti-inflammatory, hepatocarcinogenesis, antiviral, and interferon-inducing activities. This study is the first attempt to investigate the binding of GL and GA with DNA.
Shohreh, Nafisi   +3 more
openaire   +2 more sources

Selective inhibition of 11β-hydroxysteroid dehydrogenase 1 by 18α-glycyrrhetinic acid but not 18β-glycyrrhetinic acid

The Journal of Steroid Biochemistry and Molecular Biology, 2009
Elevated cortisol concentrations have been associated with metabolic diseases such as diabetes type 2 and obesity. 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1, catalyzing the conversion of inactive 11-ketoglucocorticoids into their active 11beta-hydroxy forms, plays an important role in the regulation of cortisol levels within specific ...
Classen-Houben, D.   +6 more
openaire   +2 more sources

Prolonged Administration of Glycyrrhetinic Acid in Rats

Journal of Pharmaceutical Sciences, 1964
Prolonged administration of glycyrrhetinic acid was studied in immature female rats, castrated male donor parabionts, and mature cyclic rats. Glycyrrhetinic acid treatment for 7 days interfered with the uterotrophic response of immature rats to estradiol benzoate but had no effect on the pituitary-ACTH content.
openaire   +2 more sources

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