Results 81 to 90 of about 2,522,082 (192)

The role of gap junctions composed of connexin 43 on the anti-tumor effect induced by etoposide

Zhongguo aizheng zazhi, 2015
Background and purpose: Gap junctions(GJ) could enhance cytotoxicity induced by chemotherapeutic agents. However, whether or not GJ composed of connexin 43 (Cx43) could increase etoposide cytotoxicity remains unclear. The aim of this study was to explore
汪灵芝, 彭建新
doaj  

Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice

Frontiers in Physiology, 2018
Development of spider veins is caused by the remodeling of veins located in the upper dermis and promoted by risk factors such as obesity or pregnancy that chronically increase venous pressure.
Hanna Kuk, Caroline Arnold, Andreas H. Wagner, Markus Hecker, Carsten Sticht, Thomas Korff, Thomas Korff   +6 more
doaj   +1 more source

(3β,18β,20β)-N-Ethoxycarbonylmethyl-3-nitrato-11-oxoolean-12-ene-29-carboxamide methanol monosolvate

Acta Crystallographica Section E, 2012
The title compound, C34H52N2O7·CH4O, is the methanol solvate of a difunctionalized derivative of the therapeutic agent 18β-glycyrrhetinic acid, a pentacyclic triterpene. The five six-membered rings of the glycyrrhetinic acid moiety show
Laszlo Czollner, Ulrich Jordis, Kurt Mereiter   +2 more
doaj   +1 more source

The Pharmacological Activities of Glycyrrhizinic Acid (“Glycyrrhizin”) and Glycyrrhetinic Acid

, 2018
Glycyrrhizin or, more correctly, Glycyrrhizinic acid is a triterpenoid saponin obtained from the root and rhizome extracts of Licorice (Glycyrrhiza glabra), being commonly used as a sweetener, being reported as – at least – 30 times sweeter than sucrose.
Graebin, Cedric Stephan; id_orcid, Cedric Stephan Graebin   +1 more
core   +1 more source

Outcomes in patients with nonerosive reflux disease treated with a proton pump inhibitor and alginic acid ± glycyrrhetinic acid and anthocyanosides

Clinical and Experimental Gastroenterology, 2013
Francesco Di Pierro,1 Mario Gatti,2 Giuliana Rapacioli,3 Leandro Ivaldi4 1Velleja Research, Milan, 2Gastroenterology Department, Giussano Hospital, Monza-Brianza, 3AIOR, Piacenza, 4Digestive Endoscopic Department, Ceva Hospital, Ceva, Cuneo, Italy ...
Di Pierro F, Gatti M, Rapacioli G, Ivaldi L   +3 more
doaj  

Glycyrrhetinic acid-modified chitosan nanoparticles enhanced the effect of 5-fluorouracil in murine liver cancer model via regulatory T-cells [Retraction]

Drug Design, Development and Therapy, 2014
Cheng M, Xu H, Wang Y, et al. Drug Des Devel Ther. 2013;7:1287–1299. It has come to the notice of this journal that the published paper:Cheng M, Xu H, Wang Y, et al.
Cheng M, Xu H, Wang Y, Chen H, He B, Gao X, Li Y, Han J, Zhang Z   +8 more
doaj  

A VALIDATED ISOCRATIC RP-HPLC METHOD FOR CONCURRENT ESTIMATION OF GYMNEMAGENIN, GALLIC ACID AND 18Î’-GLYCYRRHETINIC ACID IN POLYHERBAL FORMULATION [PDF]

, 2014
Objective: To develop and validate a simple, precise, selective, and accurate reversed phase high performance liquid chromatography method for concurrent analysis of gymnemagenin, gallic acid and 18β-glycyrrhetinic acid in polyherbal formulation ...
Gabhe, Satish Yashwant, Pawar, Pravin Devidas, Mahadik, Kakasaheb Ramoo, Potawale, Sachin Eknath   +3 more
core   +1 more source

Pharmacological underlying mechanisms of the anticancer effect of licorice: Bioinformatics and experimental verification

Journal of Holistic Integrative Pharmacy
Purpose: Cancer is the second leading cause of human mortality and has rapidly become a major global issue. According to traditional Chinese medicine (TCM) theory, the primary pathogenesis of cancer is the deficiency of ''vital Qi''.
Mengqi Liu, Lingping Fu, Hao Fu, Yu Chen, Mengxia Wu, Hanchun Liu   +5 more
doaj   +1 more source

Synthesis and Characterization of Star-Shaped Block Copolymer sPCL-b-PEG-GA

Advances in Materials Science and Engineering, 2014
Compared to linear polymers with the same molecular weight, star-shaped polymers have the superiority of drug loading and delivery. The glycyrrhetinic acid (GA) from licorice is remarkably characteristic of liver distribution and liver cells ...
Yi Zhang, Qian Zhao, Hewei Shao, Shiyu Zhang, Xiaoyan Han   +4 more
doaj   +1 more source

GLYCYRRHETINIC ACID AND ITS DERIVATIVES: CHEMICAL PROPERTIES, STRUCTURAL FEATURES AND BIOLOGICAL SIGNIFICANCE

Glycyrrhetinic acid is a pentacyclic triterpenoid compound obtained through the hydrolysis of glycyrrhizin, the major bioactive component of licorice (Glycyrrhiza glabra). Due to its unique chemical structure and diverse functional groups, glycyrrhetinic
Kholboeva, Madina
core   +1 more source