Results 11 to 20 of about 5,898,960 (197)

Genomic and transcriptomics analysis reveal putative secreted proteins expressed of Pasteurella multocida during 18β-glycyrrhetinic acid treatment [PDF]

Frontiers in Veterinary Science
Pasteurella multocida is a gram-negative opportunistic pathogen that can infect both domestic animals and humans, leading to large economic losses to the livestock industry. 18β-Glycyrrhetinic acid, the main active component of Glycyrrhiza glabra L., has
Zhongyuan Wu, Yuhan Zhang, Luyao Wang, Meng Mei, Yinsheng Qiu, Yu Liu, Shulin Fu, Jianglin Xiong, Qirong Lu, Pu Guo   +9 more
doaj   +2 more sources

Reengineering glycyrrhetinic acid into a therapeutic oligomer for targeted tumor therapy with cardioprotection [PDF]

Journal of Nanobiotechnology
To overcome the inherent limitations of conventional nanocarriers such as therapeutic inefficacy and suboptimal drug loading capacity, a novel “polymeric nanodrug” strategy was developed.
Zixin Wang, Bo Su, Alu Ouyang, ZiXuan Liang, Pingyun Yuan, Xin Qin, Yu Li, Xuejing Huang, Ling Fan, Hongwei Guo, Ronghua Jin   +10 more
doaj   +2 more sources

1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid [PDF]

Acta Crystallographica Section E, 2009
The title compound [systematic name: 11-oxo-2,3-(oxydinitrilo)olean-12-en-29-oic acid], C30H42N2O4, contains a linear array of five six-membered rings and a five-membered heterocyclic ring.
Jun Hu, Libing Yu, Ruji Wang, Yong Ju
doaj   +3 more sources

Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuR [PDF]

Frontiers in Pharmacology, 2019
Glycyrrhetinic acid (GA) is one of the main components of the traditional Chinese medicine of licorice, which can coordinate and promote the effects of other medicines in the traditional prescription.
Gang Chen, Bei Bei, Yuan Feng, Xuezheng Li, Zhe Jiang, Jian-Yong Si, De-Gang Qing, Juan Zhang, Juan Zhang, Ning Li   +9 more
doaj   +3 more sources

Novel 18β-glycyrrhetinic acid amide derivatives show dual-acting capabilities for controlling plant bacterial diseases through ROS-mediated antibacterial efficiency and activating plant defense responses

Journal of Integrative Agriculture, 2023
Natural products have long been a crucial source of, or provided inspiration for new agrochemical discovery. Naturally occurring 18β-glycyrrhetinic acid shows broad-spectrum bioactivities and is a potential skeleton for novel drug discovery.
Ying-lian SONG, Hong-wu LIU, Yi-hong YANG, Jing-jing HE, Bin-xin YANG, Lin-li YANG, Xiang ZHOU, Li-wei LIU, Pei-yi WANG, Song YANG   +9 more
doaj   +1 more source

In vitro anthelmintic activity of an aqueous extract of Glycyrrhiza glabra and of glycyrrhetinic acid against gastrointestinal nematodes of small ruminants

Parasite, 2021
This study evaluated the in vitro anthelmintic activity of a liquorice (Glycyrrhiza glabra) root aqueous extract and of glycyrrhetinic acid at 30, 10, 5, 1, and 0.5 mg/mL against sheep gastrointestinal nematodes (GINs), using the egg hatch test (EHT ...
Maestrini Michela, Molento Marcelo Beltrão, Forzan Mario, Perrucci Stefania   +3 more
doaj   +1 more source

Maillard and Hydrolytic Reactions in Subcritical Water Extraction of Bioactive Compounds from Licorice

Molecules, 2022
Nowadays, subcritical water extraction (SWE) techniques are extensively investigated worldwide, while the thermal reactions that inevitably occur under subcritical water conditions are rarely studied.
Rui Fan, Yanxiang Gao
doaj   +1 more source

Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity

Molecules, 2021
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water.
Wei-Yan Quan, Song-Zhi Kong, Si-Dong Li, Hua-Zhong Liu, Qian-Qian Ouyang, Yong-Mei Huang, Hui Luo   +6 more
doaj   +1 more source

Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

Molecules, 2023
Acetylated triterpenoids betulin, oleanolic acid, ursolic acid, and glycyrrhetinic acid were converted into their succinyl-spacered acetazolamide conjugates.
Toni C. Denner, Niels Heise, Julian Zacharias, Oliver Kraft, Sophie Hoenke, René Csuk   +5 more
doaj   +1 more source

Rosmarinic and Glycyrrhetinic Acid-Modified Layered Double Hydroxides as Functional Additives for Poly(Lactic Acid)/Poly(Butylene Succinate) Blends

Molecules, 2023
Immobilizing natural antioxidant and biologically active molecules in layered double hydroxides (LDHs) is an excellent method to retain and release these substances in a controlled manner, as well as protect them from thermal and photochemical ...
F. Cicogna, E. Passaglia, M. Benedettini, W. Oberhauser, Randa Ishak, F. Signori, S. Coiai   +6 more
semanticscholar   +1 more source