Topical adhesive spatio-temporal nanosystem co-delivering chlorin e6 and HMGB1 inhibitor glycyrrhizic acid for <i>in situ</i> psoriasis chemo-phototherapy. [PDF]
Acta Pharm Sin BSu L +8 more
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Fabrication and in vitro/vivo evaluation of quercetin nanocrystals stabilized by glycyrrhizic acid for liver targeted drug delivery. [PDF]
Int J Pharm XShen B +6 more
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New findings on the antagonism of the environmental chemical toxicity 2-ethylhexyl diphenyl phosphate: Glycyrrhizic acid as an Nrf2 activator targets Nrf2/ROS/STAT3 signalling crosstalk to alleviate thymic injury in chicks. [PDF]
Poult SciLuo L +5 more
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Glycyrrhizic acid aggregates seen from a synthetic surfactant perspective.
Phys Chem Chem PhysFischer P, Lutz-Bueno V.
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Aggregate formation of glycyrrhizic acid
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016Abstract Glycyrrhizic acid is derived from the licorice root. The compound is amphiphilic with a large hydrophobic aglycone group, and two glucuronic acids and a carboxyl group constituting the hydrophilic part. Therefore, glycyrrhizic acid can form aggregates or lower the surface tension of aqueous solutions owing to its specific amphiphilic ...
Tomokazu Yoshimura, Keisuke Matsuoka
exaly +2 more sources
Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid
Current Medicinal Chemistry, 2020Licorice (Glycyrrhiza glabra L.) is widely regarded as an important medicinal plant and has been used for centuries in traditional medicine because of its therapeutic properties. Studies have shown that metabolites isolated from licorice have many pharmacological activities, such as antiinflammatory, anti-viral, participation in immune regulation ...
Hai-Liang Zhu, , Kun Chen
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Glycyrrhizic acid: the assessment of a no effect level
Human and Experimental Toxicology, 2000Because from earlier experiments in rats and a pilot study in humans a no effect level of glycyrrhizic acid could not be established, a second experiment was performed in healthy volunteers. The experiment was performed in females only, because the effects were most marked in females in the pilot study.
W Van Dokkum
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Extraction of Glycyrrhizic Acid and Glabridin from Licorice [PDF]
International Journal of Molecular Sciences, 2008 The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50°C. The extracts
Kyung Ho Row +2 more
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Research Progress of Glycyrrhizic Acid on Antiviral Activity
Mini-Reviews in Medicinal Chemistry, 2019Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and hepatoprotective effects. GA has been used in the clinical treatment of hepatitis, bronchitis, gastric ulcer, AIDS (acquired immunodeficiency syndrome), certain ...
Zhi-Gang Sun +2 more
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Antiviral activity of glycyrrhizic acid
Experientia, 1980Glycyrrhizic acid inhibits the growth of several DNA and RNA viruses in cell cultures and inactivates Herpes simplex 1 virus irreversibly.
R, Pompei +4 more
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