Results 131 to 140 of about 5,199 (177)

Reduction of glycyrrhizic acid

Russian Chemical Bulletin, 1997
The reduction of glycyrrhizic acid by NaBH4 and LiAlH4 was studied. The conditions for the selective reduction of the COOH groups of the carbohydrate chain and the C(11)=0 group of aglycon were found.
L. A. Baltina, N. G. Serdyuk, E. V. Vasil’eva, G. A. Tolstikov   +3 more
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Effect of Glycyrrhizic Acid on Lappaconitine Phototransformation

The Journal of Physical Chemistry B, 2007
1H NMR and CIDNP methods were used to demonstrate that triterpene glycoside (glycyrrhizic acid, GA) can substantially change the efficiency and direction of phototransformation of alkaloid lappaconitine (LA) due to both its solubilization in GA micelles and protonation of LA amine nitrogen in water-alcohol solutions.
Valeria S, Kornievskaya, Alexander I, Kruppa, Nicholas E, Polyakov, Tatyana V, Leshina   +3 more
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Some properties of glycyrrhizic acid

Chemistry of Natural Compounds, 1994
The chemical and spectral properties of crystalline specimens of glycyrrhizic acid and its monoammonium salt have been studied. On the basis of1H and13C NMR results, diagnostic parameters of the 18β/18α-epimers have been revealed, and features of the structure of the carbohydrate moiety of these compounds are discussed.
G. G. Zapesochnaya, E. N. Zvonkova, V. A. Kurkin, E. V. Kazakova, L. N. Pervykh, B. I. Sheichenko, V. A. Bykov   +6 more
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Glycyrrhizic acid and its hydrolysate as mineralocorticoid agonist

Journal of Steroid Biochemistry, 1987
Mineralocorticoid activity of glycyrrhetinic acid (GR) was studied in vivo (electrical potential difference in rat rectum) and in vitro (brush border Mg2+-HCO3- ATPase in rat small intestine, kidney cytosol binding of GR with and without RU-28362, anti-glucocorticoid compound) in order to clarify the mechanism of mineralocorticoid-like activity of GR ...
R, Takeda, I, Miyamori, R, Soma, T, Matsubara, M, Ikeda   +4 more
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Self-assembly in saponin mixtures: Escin/tea, tea/glycyrrhizic acid, and escin/glycyrrhizic acid mixtures

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021
Abstract Saponins are plant based biosurfactants that are obtained from a wide variety of plant species. They are surface active glycosides with a hydrophobic group, which is commonly a triterpenoid or steroidal group, and saccharide hydrophilic units.
I.M. Tucker, A. Burley, R.E. Petkova, S.L. Hosking, J.R.P. Webster, P.X. Li, K. Ma, J. Doutch, J. Penfold, R.K. Thomas   +9 more
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Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone

American Journal of Physiology-Endocrinology and Metabolism, 1992
The apparent mineralocorticoid excess syndrome of patients ingesting large amounts of licorice or its derivatives is thought to be caused by the antagonism by these compounds of the enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD). 11 beta-HSD inactivates cortisol and corticosterone, allowing the more abundantly produced glucocorticoids access
E P, Gomez-Sanchez, C E, Gomez-Sanchez
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[Glycyrrhizic acid].

Bioorganicheskaia khimiia, 1998
The specific properties, chemical transformations, and biological activity of glycyrrhizic acid and its derivatives are discussed. Particular attention is paid to investigations that hold promise for the development of important drugs for clinical use.
G A, Tolstikov, L A, Baltina, E E, Shul'ts, A G, Pokrovskił   +3 more
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Isolating and Purification Technologies for Glycyrrhizic Acid

Journal of Separation Science
ABSTRACT Glycyrrhizic acid (GA) is the primary active component of the traditional Chinese medicinal herb licorice. It possesses antimicrobial, anti‐inflammatory, and antitumor activities. In addition, due to its unique sweetness, it can also be used as a food additive.
Meng, Zhao, Qing, Wang, Yun, Yang, Lanlan, Sun, Xue-Song, Gu, Chang-Jiang-Sheng, Lai   +5 more
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Glycyrrhizic acid in liquorice—Evaluation of health hazard

Food and Chemical Toxicology, 1993
Literature on case reports, clinical studies and biochemical mechanisms of the sweet-tasting compound glycyrrhizic acid in liquorice was critically reviewed to provide a safety assessment of its presence in liquorice sweets. A high intake of liquorice can cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood ...
F C, Størmer, R, Reistad, J, Alexander
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New Amino-Acid Conjugates of Glycyrrhizic Acid

Chemistry of Natural Compounds, 2014
New conjugates of glycyrrhizic acid (GA) containing two amino-acid methyl esters (4-aminobutanoic, 6-aminohexanoic, 11-aminoundecanoic) were synthesized by the activated-ester method using N-hydroxysuccinimide (HOSu)-N,N′-dicyclohexylcarbodiimide (DCC).
L. A. Baltina, O. V. Stolyarova, L. A. Baltina, R. M. Kondratenko, V. A. Fedorova, Ya. A. Orshanskaya, V. V. Zarubaev   +6 more
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