Results 171 to 180 of about 2,494,579 (210)

[Glycyrrhizic acid].

Bioorganicheskaia khimiia, 1998
The specific properties, chemical transformations, and biological activity of glycyrrhizic acid and its derivatives are discussed. Particular attention is paid to investigations that hold promise for the development of important drugs for clinical use.
G A, Tolstikov, L A, Baltina, E E, Shul'ts, A G, Pokrovskił   +3 more
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Glycyrrhizic acid and its hydrolysate as mineralocorticoid agonist

Journal of Steroid Biochemistry, 1987
Mineralocorticoid activity of glycyrrhetinic acid (GR) was studied in vivo (electrical potential difference in rat rectum) and in vitro (brush border Mg2+-HCO3- ATPase in rat small intestine, kidney cytosol binding of GR with and without RU-28362, anti-glucocorticoid compound) in order to clarify the mechanism of mineralocorticoid-like activity of GR ...
R, Takeda, I, Miyamori, R, Soma, T, Matsubara, M, Ikeda   +4 more
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Glycyrrhizic acid in liquorice—Evaluation of health hazard

Food and Chemical Toxicology, 1993
Literature on case reports, clinical studies and biochemical mechanisms of the sweet-tasting compound glycyrrhizic acid in liquorice was critically reviewed to provide a safety assessment of its presence in liquorice sweets. A high intake of liquorice can cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood ...
F C, Størmer, R, Reistad, J, Alexander
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Quercetin nanocrystals stabilized by glycyrrhizic acid for liver targeted drug delivery: impact of glycyrrhizic acid concentrations

Pharmaceutical Development and Technology
The purpose of this study was to investigate the impact of glycyrrhizic acid (GL) concentrations on in vitro and in vivo behavior of quercetin (QT) nanocrystals stabilized by GL (QT-NCs/GL), with a particular focus on its influence on liver targeted drug delivery.
Fengxia, Wang, Chengying, Shen, Fangwen, Chen, Jinyun, Cao, Pengfei, Yue, Baode, Shen   +5 more
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Study on the Electrochemical Behavior of Glycyrrhizic Acid

Journal of Electrochemistry, 1997
The electrochemical response characteristics of glycyrrhizic acid (GA) on the mercury electrode are described. In Britton Robinson buffer, the cyclic voltammograms exhibit two reduction peaks at a potential range of -0.80～-1.60 V. The peak potentials and currents change significantly when solution pH changes.
Chunming Wang, Yanrong Zhang, Hulin Li
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Final Report on the Safety Assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate1

International Journal of Toxicology, 2007
Glycyrrhetinic Acid and its salts and esters and Glycyrrhizic Acid and its salts and esters are cosmetic ingredients that function as flavoring agents or skin-conditioning agents—miscellaneous or both. These chemicals may be isolated from licorice plants.
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Membrane-modifying activity of glycyrrhizic acid

Russian Chemical Bulletin, 2015
Owing to amphiphilicity, glycyrrhizic acid is capable of forming complexes with a variety of hydrophobic therapeutic compounds. This is accompanied by a significant decrease in the therapeutic dose of the drug. In addition, glycyrrhizic acid has a strong influence on the permeability and elasticity of cell membranes.
O. Yu. Selyutina, I. E. Apanasenko, N. E. Polyakov   +2 more
openaire   +1 more source

Glycyrrhizic acid: novel potential protein targets

Biomeditsinskaya Khimiya
To date, a large body of data has been accumulated on the biological activity of a low-toxic natural glycoside, glycyrrhizic acid (GA), but the mechanism of its action at the molecular level has not been fully studied. Expanding knowledge about the spectrum of cellular protein targets of GA contributes to understanding new features of pharmacodynamics.
P V, Ershov, E O, Yablokov, L A, Kaluzhskiy, Yu V, Mezentsev, O V, Gnedenko, M A, Konstantinov, I Yu, Toropygin, A S, Ivanov   +7 more
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ChemInform Abstract: Reduction of Glycyrrhizic Acid.

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
L. A. BALTINA, N. G. SERDYUK, E. V. VASIL'EVA, G. A. TOLSTIKOV   +3 more
openaire   +1 more source

[Preparation of evodiamine-glycyrrhizic acid micelles with glycyrrhizic acid as carrier and their anti-hepatic fibrosis activity].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
This study aimed to prepare evodiamine-glycyrrhizic acid(EVO-GL) micelles to enhance the anti-hepatic fibrosis activity of evodiamine. Firstly, EVO-GL micelles were prepared with use of thin film dispersion method. With particle size, encapsulation efficiency, loading capacity of micelles and the solubility of evodiamine as the indexes, the effect of ...
Ying-Guang, Deng, Xue-Li, Lyu, Yao-Lu, Zhu, Shi-Chang, Zhang, Si-Jia, Liu, Bo-Xin, Zhao, Guo-Feng, Li   +6 more
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