Results 181 to 190 of about 6,369 (223)
Some of the next articles are maybe not open access.
Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone
American Journal of Physiology-Endocrinology and Metabolism, 1992The apparent mineralocorticoid excess syndrome of patients ingesting large amounts of licorice or its derivatives is thought to be caused by the antagonism by these compounds of the enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD). 11 beta-HSD inactivates cortisol and corticosterone, allowing the more abundantly produced glucocorticoids access
E P, Gomez-Sanchez, C E, Gomez-Sanchez
openaire +2 more sources
Isolating and Purification Technologies for Glycyrrhizic Acid
Journal of Separation ScienceABSTRACTGlycyrrhizic acid (GA) is the primary active component of the traditional Chinese medicinal herb licorice. It possesses antimicrobial, anti‐inflammatory, and antitumor activities. In addition, due to its unique sweetness, it can also be used as a food additive. Traditional Chinese medicines are typically used directly as drugs.
Meng, Zhao +5 more
openaire +2 more sources
ChemInform Abstract: Reduction of Glycyrrhizic Acid.
ChemInform, 1997AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
L. A. BALTINA +3 more
openaire +1 more source
Glycyrrhizic acid and its hydrolysate as mineralocorticoid agonist
Journal of Steroid Biochemistry, 1987Mineralocorticoid activity of glycyrrhetinic acid (GR) was studied in vivo (electrical potential difference in rat rectum) and in vitro (brush border Mg2+-HCO3- ATPase in rat small intestine, kidney cytosol binding of GR with and without RU-28362, anti-glucocorticoid compound) in order to clarify the mechanism of mineralocorticoid-like activity of GR ...
R, Takeda +4 more
openaire +2 more sources
Research Progress of Glycyrrhizic Acid on Antiviral Activity
Mini-Reviews in Medicinal Chemistry, 2019Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and hepatoprotective effects. GA has been used in the clinical treatment of hepatitis, bronchitis, gastric ulcer, AIDS (acquired immunodeficiency syndrome), certain ...
Zhi-Gang, Sun +4 more
openaire +2 more sources
Glycyrrhizic acid in liquorice—Evaluation of health hazard
Food and Chemical Toxicology, 1993Literature on case reports, clinical studies and biochemical mechanisms of the sweet-tasting compound glycyrrhizic acid in liquorice was critically reviewed to provide a safety assessment of its presence in liquorice sweets. A high intake of liquorice can cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood ...
F C, Størmer, R, Reistad, J, Alexander
openaire +2 more sources
A Natural Glycyrrhizic Acid‐Tailored Light‐Responsive Gelator
Chemistry – An Asian Journal, 2018AbstractThe construction of stimuli‐responsive materials by using naturally occurring molecules as building blocks has received increasing attention owing to their bioavailability, biocompatibility, and biodegradability. Herein, a symmetrical azobenzene‐functionalized natural glycyrrhizic acid (trans‐GAG) was synthesized and could form stable ...
Heshu Fang +4 more
openaire +2 more sources
Pharmaceutical Development and Technology
The purpose of this study was to investigate the impact of glycyrrhizic acid (GL) concentrations on in vitro and in vivo behavior of quercetin (QT) nanocrystals stabilized by GL (QT-NCs/GL), with a particular focus on its influence on liver targeted drug delivery.
Fengxia, Wang +5 more
openaire +2 more sources
The purpose of this study was to investigate the impact of glycyrrhizic acid (GL) concentrations on in vitro and in vivo behavior of quercetin (QT) nanocrystals stabilized by GL (QT-NCs/GL), with a particular focus on its influence on liver targeted drug delivery.
Fengxia, Wang +5 more
openaire +2 more sources
Antiviral Properties of Glycyrrhizic Acid and its Semisynthetic Derivatives
Mini-Reviews in Medicinal Chemistry, 2009Some natural triterpenes exert a definite antiviral activity on several human viruses. New synthetic derivatives of glycyrrhizic acid (GL) are even more active than the parental molecule. GL can alter the expression of viral genes involved in cell transformation, thus opening a new window for speculating on viral cancerogenesis.
POMPEI, RAFFAELLO +2 more
openaire +3 more sources
Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid
Current Medicinal Chemistry, 2020Licorice (Glycyrrhiza glabra L.) is widely regarded as an important medicinal plant and has been used for centuries in traditional medicine because of its therapeutic properties. Studies have shown that metabolites isolated from licorice have many pharmacological activities, such as antiinflammatory, anti-viral, participation in immune regulation ...
Kun Chen +3 more
openaire +2 more sources