Results 41 to 50 of about 13,136 (253)

Identification of the Mechanism of Matrine Combined with Glycyrrhizin for Hepatocellular Carcinoma Treatment through Network Pharmacology and Bioinformatics Analysis

open access: yesOxidative Medicine and Cellular Longevity, 2022
Matrine and glycyrrhizin are representative active ingredients of traditional Chinese medicine (TCM) used in clinical practice. Studies have demonstrated that matrine has antitumor pharmacological effects and that glycyrrhizin protects liver function ...
Tao Han   +6 more
semanticscholar   +1 more source

Evaluation of the Immunity Activity of Glycyrrhizin in AR Mice

open access: yesMolecules, 2012
In this study, we evaluated effect of glycyrrhizin on immunity function in allergic rhinitis (AR) mice. The AR mice model were induced by dripping ovalbumin in physiological saline (2 mg mL−1, 10 μL) into the bilateral nasal cavities using a micropipette.
Ai-Guo Zhou, Xiao-Lan Li
doaj   +1 more source

Physiological correlation between glycyrrhizin, glycyrrhizin‐binding lipoxygenase and casein kinase II [PDF]

open access: yesFEBS Letters, 1996
By means of glycyrrhizin (GL)‐affinity column chromatography, a GL‐binding lipoxygenase (gbLOX) was selectively purified from the partially purified soybean LOX‐1 fraction. Polypeptide analysis of the purified gbLOX by SDS‐PAGE detected two distinct polypeptides (p96 and p94), which were identical to LOX‐3 as determined by their partial N‐terminal ...
Shimoyama, Yoshihito   +5 more
openaire   +2 more sources

Research progress of glycyrrhizin in the treatment of osteoarthritis

open access: yesKouqiang hemian waike zazhi
Glycyrrhizin is extracted from licorice root and has anti-inflammatory, antioxidant, anti-tumor, anti-viral and other effects. At present, there are few studies on the role and mechanism of glycyrrhizin in osteoarthritis.
HU Zhihui, LONG Xing
doaj   +1 more source

Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2023
Pexidartinib offered a new therapeutic option for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) who were refractory to surgical treatment and had severe morbidity or functional limitations. Meanwhile, the metabolism of pexidartinib
Yanding Su   +5 more
doaj   +1 more source

The State-of-the-Art Antibacterial Activities of Glycyrrhizin: A Comprehensive Review

open access: yesMicroorganisms
Licorice (Glycyrrhiza glabra) is a plant of the genus Glycyrrhiza in the family Fabaceae/Leguminosae and is a renowned natural herb with a long history of medicinal use dating back to ancient times.
Ru-Yi Chen   +8 more
semanticscholar   +1 more source

Application of Monoclonal Antibodies against Bioactive Natural Products: Eastern Blotting and Preparation of Knockout Extract

open access: yesInternational Journal of Analytical Chemistry, 2012
Matrix-assisted laser desorption/ionization (MALDI) tof mass spectrometry was used for the confirmation of hapten number in synthesized antigen. As application of MAb, the MAbs against ginsenosides and glycyrrhizin have been prepared resulting in the ...
Hiroyuki Tanaka   +8 more
doaj   +1 more source

Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model

open access: yesJournal of Immunology Research, 2014
Upregulated TLRs are observed in the serum of animals following experimental subarachnoid hemorrhage. This study was to examine glycyrrhizin’s effect on proinflammatory cytokines and TLRs in SAH rats.
Chih-Zen Chang   +2 more
doaj   +1 more source

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah   +5 more
doaj   +1 more source

Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer

open access: yesInternational Journal of Molecular Sciences, 2021
Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 signaling.
Guifeng Wang   +6 more
semanticscholar   +1 more source

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