Results 41 to 50 of about 14,063 (274)
Glycyrrhizin Attenuates Toll Like Receptor-2, -4 and Experimental Vasospasm in a Rat Model
Journal of Immunology Research, 2014 Upregulated TLRs are observed in the serum of animals following experimental subarachnoid hemorrhage. This study was to examine glycyrrhizin’s effect on proinflammatory cytokines and TLRs in SAH rats.
Chih-Zen Chang +2 more
doaj +1 more source
, 2005 Glycyrrhizin is a triterpenoid saponin found in Glychyrrhiza glabra (licorice). Chemically, glycyrrhizin is a sulphated polysaccharide. It is considered to the active constituent of the drug and the standardization of licorice is based on glycyrrhizin ...
Singh, Amrit Pal
core +1 more source
Macromolecular Materials and Engineering, EarlyView.Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero +3 more
wiley +1 more source
Journal of Saudi Chemical Society, 2022 Background: Mitochondrial plays a vital role in regulating obesity and related comorbidity. Targeting mitochondrial function could be a potent therapeutic approach to inhibit metabolic-related diseases like obesity, liver disease.
Md. Reyad-ul-Ferdous +2 more
doaj +1 more source
Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. [PDF]
, 2017 Despite being an invaluable chemotherapeutic agent for several types of cancer, the clinical utility of doxorubicin is hampered by its age-related and dose-dependent cardiotoxicity.
Ashour, M.E. +4 more
core +1 more source
Malignancy Spectrum, EarlyView.TAE is an effective treatment for liver cancer rupture and bleeding. When treating patients with liver cancer rupture and bleeding, precise embolization is required during the TAE procedure to avoid extensive embolization. After liver cancer rupture and bleeding, a large amount of intra‐abdominal hemorrhage may induce complications such as hepatic ...
Gang Tong +3 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma
Cellular Physiology and Biochemistry, 2017 Background: Currently, there is a global attempt to identify potential anti-cancer agents with low toxicity. Previous studies have found that glycyrrhizin exerts anti-cancer action with low toxicity through suppressing thromboxane A2 (TxA2) in lung ...
Qing-Ping Deng +4 more
doaj +1 more source
Hepatotprotective Natural Products [PDF]
, 2003 Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential.
Malhotra, Samir, Singh, Amrit Pal
core +1 more source
Small Science, EarlyView.Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim +11 more
wiley +1 more source