Results 71 to 80 of about 13,136 (253)

HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin

Molecular Medicine Reports, 2021
Glycyrrhizin (GA) is the most essential active ingredient in licorice root, and has a wide range of biological and pharmacological activities. The present study aimed to conduct a detailed analysis of the effects of GA on liver cancer (LC) cell ...
Zengpeng Sun, Zhiguo Tan, C. Peng, Weimin Yi   +3 more
semanticscholar   +1 more source

Incidence Rate of Otitis Externa Episodes in Atopic Dogs Is Reduced by a Therapeutic Diet in a 6‐Month Randomised, Blinded, Controlled, Clinical Trial

Veterinary Dermatology, Volume 37, Issue 1, Page 89-102, February 2026.
ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson, Jeremy Laxalde, Franco Martini, Nina Fischer, Elisa Maina, Claude Favrot   +5 more
wiley   +1 more source

Effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism

Pharmaceutical Biology, 2018
Context: Asiatic acid has been reported to possess a wide range of pharmacological activities. Objective: This study investigates the effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism.
Ling Guo, Ying Cui, Kaijun Hao
doaj   +1 more source

Synergistic inhibitory activity of Glycyrrhizae Radix and Rubi Fructus extracts on biofilm formation of Streptococcus mutans

BMC Complementary Medicine and Therapies, 2023
Background Streptococcus mutans is a bacterium that causes oral diseases. Plaque, a biofilm produced by S. mutans and other bacteria, makes it difficult to remove cariogenic oral microorganisms, including biofilm producers.
Youngseok Ham, Tae-Jong Kim
doaj   +1 more source

Ocular Effects of Glycyrrhizin at Acidic and Neutral pH

Frontiers in Cellular and Infection Microbiology, 2022
PurposeTo test the effects of acidic vs. neutral pH glycyrrhizin (GLY) on the unwounded and wounded normal mouse cornea and after infection with Pseudomonas aeruginosa isolates KEI 1025 and multidrug-resistant MDR9.MethodsAcidic or neutral GLY vs ...
Mallika Somayajulu, Sharon A. McClellan, Denise A. Bessert, Ahalya Pitchaikannu, Linda D. Hazlett   +4 more
doaj   +1 more source

Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials [PDF]

, 2021
Yulong Wen, Yidan Tang, Miaoyue Li, Yu Lai   +3 more
openalex   +1 more source

Simultaneous Determination and Pharmacokinetic Characterization of Glycyrrhizin, Isoliquiritigenin, Liquiritigenin, and Liquiritin in Rat Plasma Following Oral Administration of Glycyrrhizae Radix Extract

Molecules, 2019
Glycyrrhizae Radix is widely used as herbal medicine and is effective against inflammation, various cancers, and digestive disorders. We aimed to develop a sensitive and simultaneous analytical method for detecting glycyrrhizin, isoliquiritigenin ...
You Jin Han, Bitna Kang, Eun-Ju Yang, Min-Koo Choi, Im-Sook Song   +4 more
doaj   +1 more source

Targeting the Spinal Cord‐Brain Axis: Electroacupuncture Mitigates Remote Frontal Cortex Neuroinflammation via HMGB1/TLR4 to Aid Functional Recovery After Spinal Cord Injury

Brain and Behavior, Volume 16, Issue 1, January 2026.
Spinal cord injury (SCI) has been shown to trigger remote neuroinflammation in the frontal cortex via the HMGB1/TLR4/NF‐κB pathway, exacerbating neural damage and impairing functional recovery. The present study demonstrates that electroacupuncture (EA) at GV4 (Mingmen) and GV14 (Dazhui) effectively mitigates this pathological cascade.
Yu Ning, Xin Hao, Phattharapon Rattanasakon, Yifei Dong, Ying Yang, Keduo Liu, Yuting Lin, Suhua Shi, Yuping Mo, Zhigang Li   +9 more
wiley   +1 more source

Comparative Phytochemical Profiles of Medicinal Plants Used for Wound Treatment: Insights From Wild and Hydroponically Cultivated Species in Lugazi Diocese, Uganda

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Medicinal plants such as Centella asiatica, Conyza sumatrensis, and Justicia betonica are widely used in Uganda for traditional wound healing. However, the impact of cultivation conditions on their therapeutic potential remains poorly understood.
Ivan Kahwa, Christina Seel, Hilda Ikiriza, Maria Kulosa, Susan Billig, Claudia Wiesner, Anke Weisheit, Olivia Harriet Makumbi, André Gerth, Leonard Kaysser   +9 more
wiley   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source