Results 51 to 60 of about 1,028 (203)

Formal Synthesis of Leustroducsin B via Reformatsky/Claisen Condensation of Silyl Glyoxylates

, 2016
A formal synthesis of leustroducsin B has been completed. The synthesis relies upon a recently developed Reformatsky/Claisen condensation of silyl glyoxylates and enantioenriched β-lactones that establishes two of the molecule’s three core stereocenters ...
Jeffrey S. Johnson (1312380), Stephen N. Greszler (2191588), Justin T. Malinowski (1878250)   +2 more
core   +1 more source

Gold‐Modified Mesoporous Carbon Enables Serum Metabolic Fingerprinting for Papillary Thyroid Carcinoma Diagnosis

Small Methods, EarlyView.
A novel MCHS‑Au‑LA substrate is developed for carbon‑gold nanostructure‐initiator mass spectrometry (C‑Au‑NIMS), which acquires metabolic fingerprints of serum samples from papillary thyroid carcinoma (PTC), benign thyroid nodules (BTN), and healthy controls (HC).
Wanwan Yi, Yida Huang, Jiayou Feng, Xiaowen Zhang, Yuheng Zhu, Kun Qian, Chang Lei, Zhongwei Lv, Chengzhong Yu   +8 more
wiley   +1 more source

Enantioselective Friedel–Crafts Reaction of Acylpyrroles with Glyoxylates Catalyzed by BINOL–Ti(IV) Complexes

, 2016
We report the first efficient enantioselective Friedel–Crafts hydroxyalkylation of pyrroles having one electron-withdrawing group at the α, β or N-positions with alkyl glyoxylates catalyzed by readily available chiral BINOL–Ti(IV) complexes (1–5 mol ...
Janusz Jurczak (1470880), Jakub Majer (2145493), Piotr Kwiatkowski (1717117)   +2 more
core   +1 more source

Silyl Glyoxylates. Conception and Realization of Flexible Conjunctive Reagents for Multicomponent Coupling [PDF]

, 2012
This Perspective describes the discovery and development of silyl glyoxylates, a new family of conjunctive reagents for use in multicomponent coupling reactions.
Steward, Kimberly M., Linghu, Xin, Malinowski, Justin T., Boyce, Gregory R., Nicewicz, David A., Satterfield, Andrew D., Schmitt, Daniel C., Greszler, Stephen N., Johnson, Jeffrey S.   +8 more
core   +1 more source

Histopathologic Characterization of Cutaneous Oxalosis Mimicking Calciphylaxis: Diagnostic Pitfalls and Polarized Light Evaluation

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous oxalosis is an uncommon manifestation of primary hyperoxalosis, which can often resemble other cutaneous manifestations of end stage renal disease (ESRD), particularly calciphylaxis. We report the case of a 46 year old female with primary hyperoxaluria type one (PH1) believed to be well‐controlled on lumasiran, a small interfering ...
Shrina Patel, Brad Graham, Kaci Reaves, Mya Phelps   +3 more
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Catalytic asymmetric Meerwein–Ponndorf–Verley reduction of glyoxylates induced by a chiral N,N′-dioxide/Y(OTf)₃complex

, 2017
An asymmetric MPV reduction of glyoxylates was for the first time achieved with excellent results and the mechanism of the reaction was probed.
Wangbin Wu, Lili Lin, Jie Ji, Baiwei Ma, Xiaohua Liu, Xiaoming Feng, Sijia Zou, Yuheng Zhang   +7 more
core   +1 more source

I. [1,2]-Brook rearrangement: application of silyl glyoxylates in a novel glycolate aldol reaction and in a controlled oligomerization to complete the total synthesis of zaragozic acid C. II. Progress toward the total synthesis of pactamycin [PDF]

, 2009
I.Symbiotic Reagent Activation: Oppenauer Oxidation of Magnesium Alkoxides by Silyl Glyoxylates Triggers Second-Stage Aldolization The treatment of silyl glyoxylates with magnesium alkoxides leads to a Meerwein-Ponndorf-Verley reduction of the silyl ...
Satterfield, Andrew Duncan
core   +1 more source

Extending the Farquhar–von Caemmerer–Berry photosynthesis model to account for various photorespiratory bypasses

New Phytologist, EarlyView.
We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin, Kaining Jin, Guoxin Chen, Tiegang Lu   +3 more
wiley   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

Plant Biotechnology Journal, EarlyView.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li, Tianshu Li, Xiaorui Xu, Jinhang Cui, Xin Chen, Jingyi Huang, Jia Song, Cui Mu, Xinyu Hong, Chunyan Liu, Ning Wang, Xue Han, Sui Wang, Qingshan Chen, Zhaoming Qi   +14 more
wiley   +1 more source