A reduction in serum IFN-γ, IL-1β, IL-6, and GM-CSF serves as potential markers for a positive outcome to lumbar epidural steroid injections. [PDF]
Chalermkitpanit P +5 more
europepmc +1 more source
GM-CSF-mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to <i>Aspergillus fumigatus</i>. [PDF]
Mills KAM +14 more
europepmc +1 more source
Elevated nitric oxide during colitis restrains GM-CSF production in ILC3 cells via suppressing an AhR-Cyp4f13-NF-κB axis. [PDF]
Zhao X +14 more
europepmc +1 more source
High-altitude hypoxia exacerbates chemotherapy-induced myelosuppression by lowering serum G-CSF/GM-CSF and regulating apoptosis and proliferation. [PDF]
Shi J +6 more
europepmc +1 more source
Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice. [PDF]
Wang J, Kong D.
europepmc +1 more source
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Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice
American Journal of Physiology-Lung Cellular and Molecular Physiology, 1999Surfactant proteins and phospholipids accumulate in the alveolar spaces and lung tissues of mice deficient in granulocyte-macrophage colony-stimulating factor (GM-CSF), with pathological findings resembling the histology seen in the human disease pulmonary alveolar proteinosis (PAP).
J A, Reed +7 more
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Incidence of GM-CSF Antibodies in Cancer Patients Receiving GM-CSF for Immunostimulation
Clinical Immunology, 2001We have assessed the immunogenicity profile of GM-CSF in patients with either colorectal carcinoma (CRC) at different stages of disease or with multiple myeloma who were given recombinant human GM-CSF (Escherichia coli-derived) combination therapy. Metastatic CRC patients received a colon carcinoma-reactive antibody and high doses of GM-CSF (425--500 ...
G, Ullenhag +8 more
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GM‐CSF and phorbol esters modulate GM‐CSF receptor expression by independent mechanisms
Journal of Cellular Physiology, 1991AbstractHuman granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) (0.1 nM) down‐modulates its receptor in IL‐3/GM‐CSF dependent M‐07e cells, in KG‐1 cells and normal granulocytes, whereas phorbol esters 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) (2 nM) down‐modulates the GM‐CSF receptor in M‐07e cells and granulocytes but not in KG‐1 cells.
BRIZZI, Maria Felice +4 more
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GM-CSF in marrow transplantation
European Journal of Cancer, 1993Bone marrow transplantation (BMT) is being increasingly used in a wide variety of diseases. During the period of re-engraftment the patient is particularly susceptible to a number of opportunistic infections which can radically affect acute morbidity and mortality.
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