Ad6-Based GM-CSF Expressing Vector Displays Oncolytic and Immunostimulatory Effects in an Immunocompetent Syrian Hamster Model of Cholangiocarcinoma. [PDF]
Zabelina DS +10 more
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Long-term survival in a patient with leptomeningeal metastases from non-small cell lung cancer treated with stereotactic radiotherapy (SRT), programmed cell death protein 1 (PD-1) inhibitor, and granulocyte-macrophage colony-stimulating factor (GM-CSF): a case report. [PDF]
Huan J, Shan C, Gu H, Li Y, Qi W.
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Engineered GM-CSF polarizes protumorigenic tumor-associated macrophages to an antitumorigenic phenotype and potently synergizes with IL-12 immunotherapy. [PDF]
Kang S +20 more
europepmc +1 more source
NOTCH1 promotes the elevation of GM-CSF and IL-6 through the EZH2/STAT3 pathway to facilitate the fibrotic state of the myocardium in DLBCL. [PDF]
Zhang H +9 more
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Reply: “Leigh Syndrome Due to the Variant c.1019T>C in COX15”
Movement Disorders Clinical Practice, EarlyView.
Haya S. AlFaris +8 more
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Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice
American Journal of Physiology-Lung Cellular and Molecular Physiology, 1999Surfactant proteins and phospholipids accumulate in the alveolar spaces and lung tissues of mice deficient in granulocyte-macrophage colony-stimulating factor (GM-CSF), with pathological findings resembling the histology seen in the human disease pulmonary alveolar proteinosis (PAP).
J A, Reed +7 more
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Incidence of GM-CSF Antibodies in Cancer Patients Receiving GM-CSF for Immunostimulation
Clinical Immunology, 2001We have assessed the immunogenicity profile of GM-CSF in patients with either colorectal carcinoma (CRC) at different stages of disease or with multiple myeloma who were given recombinant human GM-CSF (Escherichia coli-derived) combination therapy. Metastatic CRC patients received a colon carcinoma-reactive antibody and high doses of GM-CSF (425--500 ...
G, Ullenhag +8 more
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GM‐CSF and phorbol esters modulate GM‐CSF receptor expression by independent mechanisms
Journal of Cellular Physiology, 1991AbstractHuman granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) (0.1 nM) down‐modulates its receptor in IL‐3/GM‐CSF dependent M‐07e cells, in KG‐1 cells and normal granulocytes, whereas phorbol esters 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) (2 nM) down‐modulates the GM‐CSF receptor in M‐07e cells and granulocytes but not in KG‐1 cells.
BRIZZI, Maria Felice +4 more
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GM-CSF in marrow transplantation
European Journal of Cancer, 1993Bone marrow transplantation (BMT) is being increasingly used in a wide variety of diseases. During the period of re-engraftment the patient is particularly susceptible to a number of opportunistic infections which can radically affect acute morbidity and mortality.
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GM‐CSF‐induced acute eosinophilic pneumonia
British Journal of Haematology, 1995Summary. There is increasing evidence that haemopoietic growth factors are effective in reversal of neutropenia associated with large granular lymphocytes (LGLs) proliferation. A 19‐year‐old woman with CD3+/TCRγδ+, CD4−, CD8− LGL proliferation and severe neutropenia repeatedly developed blood eosinophilia, fever and dyspnoea after administration of GM‐
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