Results 71 to 80 of about 192,172 (285)

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia

Journal of Neuroinflammation, 2012
Background Microglia are resident macrophage-like cells in the central nervous system (CNS) and cause innate immune responses via the LPS receptors, Toll-like receptor (TLR) 4 and CD14, in a variety of neuroinflammatory disorders including bacterial ...
Parajuli Bijay, Sonobe Yoshifumi, Kawanokuchi Jun, Doi Yukiko, Noda Mariko, Takeuchi Hideyuki, Mizuno Tetsuya, Suzumura Akio   +7 more
doaj   +1 more source

Inhibitory mechanism of ginsenoside Rh3 on granulocyte–macrophage colony-stimulating factor expression in UV-B–irradiated murine SP-1 keratinocytes

Journal of Ginseng Research, 2020
Background: Ultraviolet (UV) goes through the epidermis and promotes release of inflammatory cytokines in keratinocytes. Granulocyte–macrophage colony-stimulating factor (GM-CSF), one of the keratinocyte-derived cytokines, regulates proliferation and ...
Young Sun Park, Ji Eun Lee, Jong Il Park, Cheol hwan Myung, Young-Ho Lim, Chae Kyu Park, Jae Sung Hwang   +6 more
doaj   +1 more source

Intracerebral administration of recombinant rabies virus expressing GM-CSF prevents the development of rabies after infection with street virus. [PDF]

PLoS ONE, 2011
Recently it was found that prior immunization with recombinant rabies virus (RABV) expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) (LBNSE-GM-CSF) resulted in high innate/adaptive immune responses and protection against challenge with
Hualei Wang, Guoqing Zhang, Yongjun Wen, Songtao Yang, Xianzhu Xia, Zhen F Fu   +5 more
doaj   +1 more source

Role of GM-CSF in lung balance and disease

Frontiers in Immunology, 2023
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor originally identified as a stimulus that induces the differentiation of bone marrow progenitor cells into granulocytes and macrophages. GM-CSF is now considered to
Yingzi Chen, Yingzi Chen, Fan Li, Fan Li, Mengqing Hua, Mengqing Hua, Meng Liang, Chuanwang Song, Chuanwang Song   +8 more
doaj   +1 more source

In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients: Implications for the establishment and maintenance of donor cell chimerism following liver transplantation [PDF]

, 1995
Dendritic cell (DC) progenitors were propagated in liquid culture from nonparenchymal cells resident in normal mouse (B10.BR; H-2k, I-E+) liver in response to granulocyte-macrophage colony stimulating factor (GM-CSF).
Fung, JJ, Li, Y, Lu, L, Qian, S, Rao, AS, Starzl, TE, Subbotin, VM, Thomson, AW   +7 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Double Blind, Randomised Controlled Trial [PDF]

, 2015
Purpose Surgical patients are at high risk for developing infectious complications and postoperative delirium. Prolonged infections and delirium result in worse outcome. Granulocyte-macrophage colony-stimulating factor (GM- CSF) and influenza vaccination
Bahra, Marcus, Haefen, Clarissa von, Lachmann, Gunnar, Luetz, Alawi, Meisel, Christian, Paupers, Marco, Renius, Markus, Schiemann, Alexander, Spies, Claudia, Wernecke, Klaus-Dieter   +9 more
core   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Sekretomodulatorische Effekte des proinflammatorischen Zytokins GM-CSF auf die Muzinsekretion an der isolierten Rattentrachea nativer und NO2-exponierter Tiere [PDF]

, 2019
Eine Facette des klinischen Erscheinungsbildes der „chronic obstructive pulmonary disease“ (COPD) ist die chronische Bronchitis mit einem überwiegend inflammatorischen Korrelat.
Krohm, Inga
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source