Results 51 to 60 of about 20,937 (267)

On improvements to CI-based GMM selection [PDF]

open access: yesInterspeech 2005, 2005
Gaussian Mixture Model (GMM) computation is known to be one of the most computation-intensive components in speech decoding. In our previous work, context-independent model based GMM selection (CIGMMS) was found to be an effective way to reduce the cost of GMM computation without significant loss in recognition accuracy.
Arthur Chan   +2 more
openaire   +1 more source

Real Time Recognition Of Speakers From Internet Audio Stream

open access: yesFoundations of Computing and Decision Sciences, 2015
In this paper we present an automatic speaker recognition technique with the use of the Internet radio lossy (encoded) speech signal streams. We show an influence of the audio encoder (e.g., bitrate) on the speaker model quality.
Weychan Radoslaw   +3 more
doaj   +1 more source

GMM Estimation with Noncausal Instruments [PDF]

open access: yesSSRN Electronic Journal, 2009
Lagged variables are often used as instruments when the generalized method of moments (GMM) is applied to time series data. We show that if these variables follow noncausal autoregressive processes, their lags are not valid instruments and the GMM estimator is inconsistent.
Lanne Markku, Saikkonen Pentti
openaire   +3 more sources

The GMM Parameter Normalization Puzzle [PDF]

open access: yesFinance and Economics Discussion Series, 1997
A feature of GMM estimation--the use of a consistent estimate of the optimal weighting matrix rather than the joint estimation of the model parameters and the weighting matrix--can lead to the sensitivity of GMM estimation to the choice of parameter normalization.
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Gut microbial metabolite functional screening platform

open access: yes生物医学转化, 2022
Human gut microbial metabolites are closely related to the physiological functions of the human body, and the exploration of the functions of these small molecules is an ongoing topic for researchers. With the development of metagenomics and metabolomics,
Li Zhunduo, Sun Hui
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Multimodal Data‐Driven Microstructure Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang   +4 more
wiley   +1 more source

Shadow Economy: Determinants and Its Impact on Foreign Direct Investment

open access: yesJIET (Jurnal Ilmu Ekonomi Terapan)
The shadow economy poses a significant threat to government revenue and the effectiveness of economic policies. This paper investigates the causes of the shadow economy and its influence on foreign direct investment (FDI).
Unggul Heriqbaldi   +1 more
doaj   +1 more source

Intermediate Resistive State in Wafer‐Scale Vertical MoS2 Memristors Through Lateral Silver Filament Growth for Artificial Synapse Applications

open access: yesAdvanced Functional Materials, EarlyView.
In MOCVD MoS2 memristors, a current compliance‐regulated Ag filament mechanism is revealed. The filament ruptures spontaneously during volatile switching, while subsequent growth proceeds vertically through the MoS2 layers and then laterally along the van der Waals gaps during nonvolatile switching.
Yuan Fa   +19 more
wiley   +1 more source

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