Results 161 to 170 of about 108,095 (254)
Objective To estimate risk of prostate‐specific antigen (PSA) relapse after radical radiotherapy (RT) for prostate cancer (PCa), and risk of PCa death after relapse according to Gleason score and time to relapse. Patients and Methods Men in the National Prostate Cancer Register of Sweden who underwent primary radical RT in 2007–2024 were followed until
Paolo Zaurito +8 more
wiley +1 more source
Homo sapiens, industrialisation and the environmental mismatch hypothesis
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Evaluating the contraceptive potential of active immunization against gonadotropin-releasing hormone. [PDF]
Urbanski HF +6 more
europepmc +1 more source
Low Testosterone in Men With Type 2 Diabetes: The Role of Estrogen Excess and Aromatase Activity
ABSTRACT Objective Low testosterone is common in men with type 2 diabetes and is associated with adverse metabolic outcomes. Our objective was to identify factors associated with low total and calculated free testosterone (CFT) in men with type 2 diabetes, with a focus on relative estrogen excess and subcutaneous adipose aromatase expression.
Nyo Nyo Z. Tun +2 more
wiley +1 more source
Management of infertility in women with hypothalamic hypogonadotropic hypogonadism: an expert opinion. [PDF]
Robin G +6 more
europepmc +1 more source
Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy
ABSTRACT Aims/Introduction Diabetic retinopathy (DR) is a prevalent chronic complication of type 2 diabetes mellitus (T2DM), contributing significantly to vision impairment. Circular RNAs (circRNAs) have emerged as key regulators in the pathogenesis of DR.
Wencheng An +9 more
wiley +1 more source
Gonadotropins Across the Lifespan: Their role in the Neurodevelopment-Neurodegeneration Continuum. [PDF]
Galbraith JA +4 more
europepmc +1 more source
Abstract The arcuate nucleus kisspeptin (ARNKISS) neurons intermittently synchronize their activity to operate as the GnRH pulse generator and drive pulsatile reproductive hormone secretion in mammals. Although ARNKISS neurons are known to receive various GABAergic inputs, the effects of GABAA and GABAB receptor modulation on their ability to ...
Toby Eddleston +2 more
wiley +1 more source
Preoptic kisspeptin-nNOS-GnRH (KiNG) neuronal network regulates LH rhythmicity through activation-inhibition in mice. [PDF]
Delli V +11 more
europepmc +1 more source

