Results 181 to 190 of about 50,034 (219)
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Use of the GnRH-agonist (GnRH-A) in gynaecology.
1998GnRH-agonist therapy is used in the management of many gynaecological pathologies: uterine fibroids, endometriosis, ovarian cystic pathology, breast cancer, dysfunctional uterine bleeding and, in males, prostatic cancer. In the case of uterine fibroids, this therapy can be used as a pre-treatment before conservative or demolitive surgery or as an ...
CIARDO A, SPINA V, ALEANDRI, Vincenzo
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Journal of Obstetric, Gynecologic & Neonatal Nursing, 1994
Gonadotropin-releasing hormone agonists are a relatively new class of drugs, which, when chronically administered, result in marked reductions in blood levels of testosterone and estrogen. These drugs include leuprolide acetate (Lupron); the first GnRH agonist to be approved in the United States, nafarelin acetate (Synarel); and goserelin acetate ...
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Gonadotropin-releasing hormone agonists are a relatively new class of drugs, which, when chronically administered, result in marked reductions in blood levels of testosterone and estrogen. These drugs include leuprolide acetate (Lupron); the first GnRH agonist to be approved in the United States, nafarelin acetate (Synarel); and goserelin acetate ...
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Embryo implantation and GnRH antagonists: GnRH antagonists do not activate the GnRH receptor.
Human reproduction (Oxford, England), 2000Recent suggestions that gonadotrophin-releasing hormone (GnRH) antagonists activate the GnRH receptor are discussed. Most of the studies cited in support of this suggestion are in-vitro studies, testing supra-pharmacological doses of GnRH analogues in cancer cell lines, whereas GnRH antagonists, e.g.
B, Mannaerts, K, Gordon
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American Journal of Obstetrics and Gynecology, 1990
The notion of an oscillator or signal generator in the central nervous system that controls the rhythmic release of GnRH and, thereby, the pulsatile secretion of the gonadotropic hormones, originated in the finding of strikingly abrupt and rhythmic fluctuations in the concentration of LH in the plasma of ovariectomized monkeys. These oscillations had a
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The notion of an oscillator or signal generator in the central nervous system that controls the rhythmic release of GnRH and, thereby, the pulsatile secretion of the gonadotropic hormones, originated in the finding of strikingly abrupt and rhythmic fluctuations in the concentration of LH in the plasma of ovariectomized monkeys. These oscillations had a
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Applications for GnRH antagonists
Trends in Endocrinology and Metabolism, 2001Abstract Meeting on the Potential Clinical Applications for Gonadotropin-Releasing Hormone Antagonists was held at the National Institutes of Health in Bethesda, MD, USA on 31 January 2001.
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GnRH AND GnRH ANALOGUES: APPLICATIONS IN GYNECOLOGY
Clinical Obstetrics and Gynecology, 1993openaire +2 more sources
GnRH and GnRH receptor genes in the human genome.
Endocrinology, 2002Four different GnRHs and one GnRH receptor are reported to be expressed in various mammals, whereas 13 GnRHs and numerous GnRH receptors have been identified in various nonmammalian vertebrates. The nucleotide sequencing of the human genome provided the opportunity to determine which of these peptides and receptors might be expressed in primates.
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