Results 71 to 80 of about 194,150 (247)

Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies:Physiological, Pathophysiological and Therapeutic Implications [PDF]

, 2012
Pulsatile gonadotropin-releasing hormone (GnRH) is crucial to normal reproductive function and abnormalities in pulse frequency give rise to reproductive dysfunction.
Young, Jacques, Millar, Robert, Brailly-Tabard, Sylvie, Guiochon-Mantel, Anne, Bouligand, Jerome, Millar, Robert P, George, Jyothis, Tello, Javier, Anderson, Richard, Francou, Bruno, Anderson, Richard A, George, Jyothis T, Tello, Javier A, Tello, Javier; id_orcid   +13 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Long-term GnRH-agonist administration revealed a GnRH-independent mechanism stimulating FSH discharge in humans

, 1996
The present study evaluated the FSH and LH episodic discharge in different physiopathological conditions undergoing chronic GnRH-agonist administration. Four girls with true precocious puberty and five postmenopausal women were administered GnRH-agonist (
Massolo F, MASSOLO, Fausta, Genazzani, Andrea R., Massolo, F., GENAZZANI, Alessandro, Genazzani A., Petraglia F, Ferrari, E., Genazzani, A. D., Gandolfi, A., GENAZZANI, ANDREA, Gandolfi, Andrea, Ferrari E, Petraglia, Felice, Petraglia, F., Gandolfi A, Ferrari, Elena, Genazzani, A. R.   +17 more
core   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2 [PDF]

, 2013
Background: More than 25% of patients diagnosed with endometrial carcinoma have an invasive primary cancer accompanied by metastases. Gonadotropin-releasing hormone (GnRH) plays an important role in reproduction.
Huang, Hong-Yuan, Wu, Hsien-Ming, Peter CK Leung, Lai, Chyong-Huey, Lee, Chyi-Long, Hsin-Shih Wang, Chyi-Long Lee, Wang, Hsin-Shih, Hong-Yuan Huang, Leung, P. C. K., Hsien-Ming Wu, Soong, Yung-Kuei, Chyong-Huey Lai, Yung-Kuei Soong   +13 more
core   +2 more sources

Beliefs about emotions, distress tolerance and paranoia across the menstrual cycle in individuals with premenstrual difficulties and controls

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Premenstrual Disorders are characterized by recurrent symptoms associated with clinically significant distress or impairment. There is limited understanding of psychological processes associated with premenstrual difficulties.
Ellen Lambert, Myra Hunter, Trudie Chalder   +2 more
wiley   +1 more source

Low-dose hCG as trigger day and 35 hr later have different ovarian hyperstimulation syndrome occurrence in females undergoing In vitro fertilization: An RCT

International Journal of Reproductive BioMedicine, 2017
Background: Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication, which can cause high morbidity and mortality. Use of gonadotropin releasing hormone (GnRH) agonist instead of human chorionic gonadotropin (hCG) in GnRH antagonist cycles
Marzieh Aghahosseini, Ashraf Aleyasin, Venus Chegini, Victoria Chegini   +3 more
doaj  

Stop gonadotropin-releasing hormone-agonist protocol not superior to antagonist protocol on the outcomes of assisted reproductive techniques in poor responders: A randomized clinical trial

International Journal of Reproductive BioMedicine
Background: Poor ovarian response remains one of the most challenging problems in assisted reproductive technology. Various stimulation protocols have been proposed to improve outcomes, including combined gonadotropin-releasing hormone (GnRH) agonist ...
Saeideh Dashti, Robab Davar, Fatemeh Emami, Farimah Shamsi, Esmat Mangoli   +4 more
doaj   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Live Birth Outcomes for PCOS Patients Under the Follicular-Phase Long-Acting GnRH Agonist Protocol or Antagonist Protocol – A Retrospective Chinese Cohort

Journal of Multidisciplinary Healthcare, 2023
Jiajia Zhai,1 Junyan Zhang,2,3 Jingfang He,3 Minzhi Lv,4,5 Bozheng Zhang,6 Guanqun Li,7 Yuanjie Du,1 Guimin Hao1 1Department of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Shanxi ...
Zhai J, Zhang J, He J, Lv M, Zhang B, Li G, Du Y, Hao G   +7 more
doaj