Results 41 to 50 of about 210,635 (269)

GnRH antagonists in the treatment of infertility

Annals of Medicine, 2003
GnRH analogues were introduced into clinical practice more than 20 years ago. The recent development of new GnRH antagonists (GnRHant) has revolutionized the treatment protocols of infertility. Ovarian stimulation has become easier, safer and more convenient for patients.
Jürgen M, Weiss, Michael, Ludwig, Olaf, Ortmann, Klaus, Diedrich   +3 more
openaire   +2 more sources

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Stop gonadotropin-releasing hormone-agonist protocol not superior to antagonist protocol on the outcomes of assisted reproductive techniques in poor responders: A randomized clinical trial

International Journal of Reproductive BioMedicine
Background: Poor ovarian response remains one of the most challenging problems in assisted reproductive technology. Various stimulation protocols have been proposed to improve outcomes, including combined gonadotropin-releasing hormone (GnRH) agonist ...
Saeideh Dashti, Robab Davar, Fatemeh Emami, Farimah Shamsi, Esmat Mangoli   +4 more
doaj   +1 more source

Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats

The Journal of Reproduction and Development, 2020
Accumulating evidence suggests that KNDy neurons located in the hypothalamic arcuate nucleus (ARC), which are reported to express kisspeptin, neurokinin B, and dynorphin A, are indispensable for the gonadotropin-releasing hormone (GnRH) pulse generation ...
Takuya SASAKI, Tomoya SONODA, Ryoki TATEBAYASHI, Yuri KITAGAWA, Shinya OISHI, Koki YAMAMOTO, Nobutaka FUJII, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Kei-ichiro MAEDA, Fuko MATSUDA, Yasuhiro MORITA, Shuichi MATSUYAMA, Satoshi OHKURA   +14 more
doaj   +1 more source

Comparison of results of controlled ovarian stimulation (initiated cycles) for patients with AMH <1.2 ng/mL between the GnRH agonist (GnRH-a) and antagonist (GnRH-ant) protocols.

, 2018
Comparison of results of controlled ovarian stimulation (initiated cycles) for patients with AMH
Ming-Chao Huang (798716), Chun-I Lee (1569778), Tsung-Hsien Lee (4495195), Maw-Sheng Lee (648070), Hsiu-Hui Chen (808410), Shu-Ling Tzeng (155077), Chun-Chia Huang (2620234)   +6 more
core   +1 more source

Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology

Advanced Intelligent Discovery, EarlyView.
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh, Raiyan Siddique, Sarah S. Sharif, Yaser Mike Banad   +3 more
wiley   +1 more source

A Patient Friendly Corifollitropin Alfa Protocol without Routine Pituitary Suppression in Normal Responders. [PDF]

PLoS ONE, 2016
The release of corifollitropin alfa simplifies daily injections of short-acting recombinant follicular stimulating hormone (rFSH), and its widely-used protocol involves short-acting gonadotropins supplements and a fixed GnRH antagonist regimen, largely ...
Huai-Ling Wang, Hsing-Hua Lai, Tzu-Hsuan Chuang, Yu-Wei Shih, Shih-Chieh Huang, Meng-Ju Lee, Shee-Uan Chen   +6 more
doaj   +1 more source

The Comparision Of Effect Of Microdose Gnrh-A Flare-Up, Gnrh Antagonist/Aromatase İnhibitor Letrozole And Gnrh Antagonist/Clomiphene Citrate Protocols On Ivf Outcomes İn Poor Responder Patients

, 2014
Purpose: To compare the effects of microdose GnRH-a flare-up, GnRH antagonist/aromatase inhibitor letrozole and GnRH antagonist/clomiphene citrate protocols on IVF outcomes in poor responder patients.
Bostancı, Mehmet Sühha, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü   +1 more
core   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Gonadotropin releasing hormone antagonist use in controlled ovarian stimulation and intrauterine insemination cycles in women with polycystic ovary syndrome

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To evaluate the effect of the GnRH antagonist on gonadotropin ovulation induction in women with PCOS. Materials and methods: A total of 175 intrauterine insemination (IUI) cycles in women with polycystic ovary syndrome (PCOS) were included in ...
Runa Ozelci, Serdar Dilbaz, Berna Dilbaz, Derya Akdag Cırık, Saynur Yılmaz, Ozlem Moraloglu Tekin   +5 more
doaj   +1 more source