Results 31 to 40 of about 357,265 (161)

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines [PDF]

, 2011
Breakthrough Breast CancerBackground: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells.
Sims Andrew H, Faratian Dana, Miller, Nicola, Sims, Andrew H., Morgan, Kevin, Miller Nicola, Millar, Robert P., Langdon, Simon P., Ilgin Cagnan, Sims, Andrew, Dana Faratian, Robert P Millar, Meyer, Colette, Simon P Langdon, Colette Meyer, Harrison David J, Cagnan, Ilgin, Nicola Miller, Morgan Kevin, Millar Robert P, David J Harrison, Faratian, Dana, Langdon Simon P, Kevin Morgan, Meyer Colette, Cagnan Ilgin, Andrew H Sims, Harrison, David J.   +27 more
core   +2 more sources

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

Effectiveness and safety of injectable human papilloma virus vaccine administered as eyedrops

, 2023
Mucosal vaccines have the advantages of ease of administration and the induction of strong mucosal immunity and a systemic immune response. Recently, the eye mucosa has been shown to be an effective and safe alternative vaccination route against ...
윤상철, 서경률, 이지혜
core   +1 more source

The role of Gai in the Gonadotropin-releasing hormone (GnRH) receptor inhibition of cell proliferation [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 72-78).The activation of Gonadotropin-releasing hormone receptor (GnRHR) by the GnRH ligand has been shown to mediate antiproliferative effects in extra-pituitary cells and in reproductive ...
Phillips, Pumza Samantha
core   +1 more source

Plasma Macro and Trace Element Levels of Female Rats Vaccinated with GnRH Hormone on Reproductive

Van Tıp Dergisi, 2018
INTRODUCTION: There is a significant relationship between hormones and trace elements. Trace elements can cause harmful and beneficial effects on animal and human life depending on their concentration.
Aslı Çilingir Yeltekin, Funda Eşki, Leyla Mis   +2 more
doaj   +1 more source

Versatile virus-like particle carrier for epitope based vaccines. [PDF]

PLoS ONE, 2010
BACKGROUND: Recombinant proteins and in particular single domains or peptides are often poorly immunogenic unless conjugated to a carrier protein. Virus-like-particles are a very efficient means to confer high immunogenicity to antigens.
Alain C Tissot, Regina Renhofa, Nicole Schmitz, Indulis Cielens, Edwin Meijerink, Velta Ose, Gary T Jennings, Philippe Saudan, Paul Pumpens, Martin F Bachmann   +9 more
doaj   +1 more source

Plasmid DNA vaccine coding eight repeats of gonadotrophin-releasing hormone induced atrophy of prostate in male mice

Prostate International, 2018
Background: Prostate hyperplasia and neoplasia are major illness of men and elderly dogs. Treatment of prostate cancer requires androgen deprivation surgery or therapy to prevent metastases and alleviate pain.
Umme K. Rima, Abu S.M. Bari, Mohammad Z. Hossain, Mohammad A.H. Khan   +3 more
doaj   +1 more source

Effects of GnRH vaccination in wild and captive African Elephant bulls (Loxodonta africana) on reproductive organs and semen quality. [PDF]

PLoS ONE, 2017
Although the African elephant (Loxodonta africana) is classified as endangered by the International Union for Conservation of Nature (IUCN), in some isolated habitats in southern Africa, contraception is of major interest due to local overpopulation ...
Imke Lueders, Debbie Young, Liana Maree, Gerhard van der Horst, Ilse Luther, Stephan Botha, Brendan Tindall, Geoffrey Fosgate, André Ganswindt, Henk J Bertschinger   +9 more
doaj   +1 more source

Veterinarian attitudes towards immunocontraceptive use in cats

Australian Veterinary Journal, EarlyView.
Background The continuously expanding global cat population poses concerns to public health, native ecosystems and individual animal welfare. These concerns have led to additional management strategies to reduce unowned cat numbers, including the development of feline immunocontraceptives.
E Vartola, S Wills, E Cottingham, CD Marth, N Krekeler   +4 more
wiley   +1 more source

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

, 2020
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core   +1 more source