Results 251 to 260 of about 200,215 (293)
Some of the next articles are maybe not open access.
Critical Care Medicine, 2004
In a single center, randomized controlled trial, EGDT has been shown to reduce mortality by 16% in patients presenting to the emergency department with sepsis or septic shock. However, widespread implementation of EGDT will require a collaborative effort between multiple disciplines (physicians, nurses, allied health personnel) as well as multiple ...
Emanuel P. Rivers +3 more
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In a single center, randomized controlled trial, EGDT has been shown to reduce mortality by 16% in patients presenting to the emergency department with sepsis or septic shock. However, widespread implementation of EGDT will require a collaborative effort between multiple disciplines (physicians, nurses, allied health personnel) as well as multiple ...
Emanuel P. Rivers +3 more
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Early Goal-directed Therapy: A Role for Echocardiography
International Journal of Perioperative Ultrasound and Applied Technologies, 2013Early goal-directed therapy has been implemented now several years. Various haemodynamic monitoring systems have been forwarded. The choice should be governed by interchangeability and consistency of data and ease of use at the bedside. The role of echocardiography has not been discussed in this respect.
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2020
Intra-operative fluid therapy is one of the most discussed and debated therapies in recent years as a result of a difficult assessment of the volume status and of the risks associated with a liberal attitude towards volume replacement.
Marta Iaconi +3 more
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Intra-operative fluid therapy is one of the most discussed and debated therapies in recent years as a result of a difficult assessment of the volume status and of the risks associated with a liberal attitude towards volume replacement.
Marta Iaconi +3 more
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The Physiology of Early Goal-Directed Therapy for Sepsis
Journal of Intensive Care Medicine, 2016In 2001, Rivers and colleagues published a randomized controlled trial of early goal-directed therapy (EGDT) for the treatment of sepsis. More than a decade later, it remains a landmark achievement. The study proved the benefits of early aggressive treatment of sepsis. However, many questions remain about specific aspects of the complex EGDT algorithm.
Lindsay, Lief +2 more
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Lifting the lid on perioperative goal-directed therapy
British Journal of Anaesthesia, 2021The complex cellular interactions that underlie pathologies related to reduced oxygen delivery after surgery are poorly defined and difficult to measure. Heywood and colleagues explored the patterns of protein expression in skin biopsies taken from a subgroup of patients enrolled in a randomised trial designed to evaluate perioperative goal-directed ...
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Perioperative goal-directed therapy
Acta Anaesthesiologica Scandinavica, 2018Background: Perioperative goal-directed therapy aims to optimise haemodynamics by titrating fluids, vasopressors and/or inotropes to predefined haemodynamic targets. Perioperative goal-directed therapy is a complex intervention composed of several independent component interventions.
Kaufmann, Thomas +5 more
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Goal Directed Therapy: A Review
2013The issue of hemodynamic optimization has attracted increasing interest over the last two decades, following publication of several studies that have suggested beneficial effects of so called “goal-directed therapy” on patient outcomes. Whereas in the past large volumes of crystalloids were administered in order to replace an ambiguous ‘third space ...
M. Gruenewald, B. Bein
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Goal-Directed Therapy of Acute Respiratory Failure
Anesthesia & Analgesia, 1980Three hundred fifteen consecutive patients with acute respiratory failure (ARF) were treated to the same end point. Based on blood gas determination, positive end-expiratory pressure (PEEP) was added in incremental steps to either maintain or reduce intrapulmonary shunt to 15%. Mean optimal PEEP level was 15.3 +/- 9.2 cm H2O.
T J, Gallagher, J M, Civetta
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