Results 21 to 30 of about 1,874,085 (267)
Objective. The purpose of the study is to identify the main causes of the growing shortage of personnel resources of territorial divisions of internal affairs bodies (ATS) and appropriate methods of their elimination.Method. When searching for the causes
A. V. Rybak, R. M. Danilov
doaj +1 more source
Re-appreciating the why of cognition: 35 years after Marr and Poggio
Marr and Poggio's levels of description are one of the most well-known theoretical constructs of 20th century cognitive science. It entails that behavior can and should be considered at three different levels: computation, algorithm, and implementation ...
Roel M Willems
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ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
During their existence, people often forget about the meaning of life. With the world spinning faster and faster, the disappearing ability to reflect on complex day-to- day life, the virtual reality and ‘the net’ jungle, people are forgetting how to ...
Michał Styczyński
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The power of Nutrition Impact and Positive Practice (NIPP) Circles
The Nutrition Impact and Positive Practice (NIPP) circle model was designed to provide alternative, community-based treatment and prevention of moderate acute malnutrition (MAM) to food-aid initiatives, including blanket supplementary feeding programmes (
Nicki Connell +2 more
doaj
Research on rock burst prediction based on an integrated model
Rockburst is a significant safety threat in coal mining, influenced by complex nonlinear dynamic characteristics and multi-factor coupling. This study proposes a rockburst risk prediction method based on the SSA-CNN-MoLSTM-Attention model.
Junming Zhang +7 more
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