Results 41 to 50 of about 11,733,399 (339)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Re-appreciating the why of cognition: 35 years after Marr and Poggio

open access: yesFrontiers in Psychology, 2011
Marr and Poggio's levels of description are one of the most well-known theoretical constructs of 20th century cognitive science. It entails that behavior can and should be considered at three different levels: computation, algorithm, and implementation ...
Roel M Willems
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Reaching a Goal [PDF]

open access: yes, 2014
Craig Ostbo \u2715 seems to have it all – a successful business, close family, community ties – and he\u27s even the drummer in the band Petty Fever. But there is one goal that has eluded him until now – completing his college degree. That will change in
Mileham, Mardi
core   +1 more source

Goal-conflict detection based on temporal satisfiability checking [PDF]

open access: yes, 2016
Goal-oriented requirements engineering approaches propose capturing how a system should behave through the speci ca- tion of high-level goals, from which requirements can then be systematically derived. Goals may however admit subtle situations that make
Anton Ana I.   +7 more
core   +1 more source

Self-Motivation for Academic Attainment: The Role of Self-Efficacy Beliefs and Personal Goal Setting

open access: yesThe American Educational Research Journal, 1992
The causal role of students’ self-efficacy beliefs and academic goals in self-motivated academic attainment was studied using path analysis procedures. Parental goal setting and students’ self-efficacy and personal goals at the beginning of the semester ...
B. Zimmerman   +2 more
semanticscholar   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Goal-based self-contextualization [PDF]

open access: yes, 2009
. System self-contextualizability is the system ability to autonomously adapt its behavior to the uncontrollable relevant context to keep its objectives satisfied.
Ali, Raian   +2 more
core   +2 more sources

The i* framework for goal-oriented modeling [PDF]

open access: yes, 2016
The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-39417-6i* is a widespread framework in the software engineering field that supports goal-oriented modeling of socio-technical systems and organizations.
Cares, Carlos   +3 more
core   +2 more sources

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