Results 31 to 40 of about 3,359,537 (313)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

RUSSIA AND GLOBAL WORLD: THE TRANSITION TO A NEW PARADIGM OF DEVELOPMENT IS INEVITABLE

open access: yesМодернизация, инновация, развитие, 2015
The article is focused on analysis of the crisis situation inRussiaand in the world. It is stated that the problems of social and economic development, acceleration of economic growth and formation of a new model cannot be solved within the frames of the
Valentina M. Bondarenko
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The power of Nutrition Impact and Positive Practice (NIPP) Circles

open access: yesSouth Sudan Medical Journal, 2013
The Nutrition Impact and Positive Practice (NIPP) circle model was designed to provide alternative, community-based treatment and prevention of moderate acute malnutrition (MAM) to food-aid initiatives, including blanket supplementary feeding programmes (
Nicki Connell   +2 more
doaj  

Research on rock burst prediction based on an integrated model

open access: yesScientific Reports
Rockburst is a significant safety threat in coal mining, influenced by complex nonlinear dynamic characteristics and multi-factor coupling. This study proposes a rockburst risk prediction method based on the SSA-CNN-MoLSTM-Attention model.
Junming Zhang   +7 more
doaj   +1 more source

Equations and Formulas as Problem Solving Strategies Frequently Used by Students in Solving Math Problems

open access: yesJPAIR Institutional Research Journal, 2014
Problem solving is the core and primary objective of mathematics teaching. This study aimed to describe the problem solving abilities of sophomore engineering students of Nueva Ecija University of Science and Technology (NEUST) through the use of case ...
Salvador A. Loria Jr.
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

MGIMO Educational Standards: Goal and Contents of Professional Language Training of IR Economics Students

open access: yesVestnik MGIMO-Universiteta, 2015
The article gives a methodological analysis of MGIMO-University own education standards and programmes. The relevance of the article is explained by the necessity to define the goals and contents of professional language training of IR economics students
Alla A. Kizima
doaj   +2 more sources

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