Results 51 to 60 of about 1,874,085 (267)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ACQUISITION OF BASIC PUBLIC SPEAKING SKILLS

open access: yesBizInfo, 2017
With this texst we show that the acquisition of oratorical skills means not only mastering certain techniques of oratory, or public speaking, but that this is largely primarily related with a kind of mental preparation of speakers themselves, or in which
Nataša Novaković, Boris Teodosijević
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

THE NATIONAL OLYMPICS FOR SCHOOL SPORTS BETWEEN DESIRE AND REALITY

open access: yesSport şi Societate, 2013
Aim. The purpose of this qualitative research is to capture to what extent the program of the competition "National School Sports Olympics" accomplishes its goals. Hypothesis. Health of the population and identifying talent follows a coherent program
Muresan Alexandru
doaj  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Teachers’ Professional Development in the Framework of the New Federal State Educational Standards

open access: yesОбразование и наука, 2015
The paper considers a contradiction between the great demand for teachers’ professional development, induced by the new Federal State Educational Standards, and the lack of relevant training programs for school teachers. The author has conducted a survey
Y. A. Sidenko
doaj   +1 more source

The Concept of Telicity in English, Romanian and Serbian

open access: yesRomanian Journal of English Studies, 2020
Given that the notion of telicity was simply defined by English linguists as a situation which tends towards a goal, this paper will additionally explain and define telicity in the English language.
Lazović Mihaela
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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