Results 61 to 70 of about 3,359,537 (313)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Attracting Human Resources to Arctic Enterprises Using Marketing Tools

open access: yesАрктика и Север, 2020
In connection with the movement of various types of production in the Arctic region, it becomes necessary to attract human resources to new enterprises. In the article, we analyze the branding system in companies operating in the Arctic region, as one of
Sofya O. PUDOVKINA, Marina N. KRUK
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

ACQUISITION OF BASIC PUBLIC SPEAKING SKILLS

open access: yesBizInfo, 2017
With this texst we show that the acquisition of oratorical skills means not only mastering certain techniques of oratory, or public speaking, but that this is largely primarily related with a kind of mental preparation of speakers themselves, or in which
Nataša Novaković, Boris Teodosijević
doaj   +1 more source

Domain independent goal recognition

open access: yes, 2010
Goal recognition is generally considered to follow plan recognition. The plan recognition problem is typically defined to be that of identifying which plan in a given library of plans is being executed, given a sequence of observed actions.
Pattison, D., Long, D.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Flags maniac

open access: yes, 2016
The software displays flags from different countries, which should be linked to their countries’ names by the studentPrevious knowledge of countriesComponente Curricular::Ensino Fundamental::Séries Iniciais::GeografiaComponente Curricular::Ensino ...
Goal maniac
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Effect of goal activation on goal management

open access: yesThe Japanese journal of psychology, 2015
Studies of goal management have examined how to manage multiple goals. Previous research (Finkelstein & Fislibach, 2010) showed that healthy eating made one hungrier. This study hypothesized that participants were hungrier when a health goal was not activated than when it was activated.
openaire   +3 more sources

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