Results 31 to 40 of about 179,728 (215)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Equations and Formulas as Problem Solving Strategies Frequently Used by Students in Solving Math Problems

open access: yesJPAIR Institutional Research Journal, 2014
Problem solving is the core and primary objective of mathematics teaching. This study aimed to describe the problem solving abilities of sophomore engineering students of Nueva Ecija University of Science and Technology (NEUST) through the use of case ...
Salvador A. Loria Jr.
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

MGIMO Educational Standards: Goal and Contents of Professional Language Training of IR Economics Students

open access: yesVestnik MGIMO-Universiteta, 2015
The article gives a methodological analysis of MGIMO-University own education standards and programmes. The relevance of the article is explained by the necessity to define the goals and contents of professional language training of IR economics students
Alla A. Kizima
doaj   +2 more sources

Investigation of crack propagation patterns on the borehole wall during single-borehole hydraulic fracturing under different in-situ stress ratios

open access: yesScientific Reports
To study the initiation, propagation, and mechanical behaviour characteristics of fractures on the wall of a single hole during hydraulic fracturing for in-situ stress measurement, and to improve the accuracy of stress direction discrimination in ...
Tan Lei   +4 more
doaj   +1 more source

A study on the approach to formal teaching of Arabic language and its influence on the selection of core vocabulary of Arabic standard language [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2010
According to Arabic language curriculum guide, Among different approaches for second  Language Teaching,  the approach of “text comprehension specially religious one” has been chosen for teaching this subject. The reasons of this choice were: the authors’
Hamid-Reza Mirhaji
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Incorporating the patient voice and patient engagement in GOAL‐Hēm: Advancing patient‐centric hemophilia care

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2022
Background Goal Attainment Scaling for Hemophilia (GOAL‐Hēm) is a novel, hemophilia‐specific, validated patient engagement tool and patient‐reported outcome instrument.
Jonathan C. Roberts   +6 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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