Results 91 to 100 of about 3,147,351 (292)
A Study on Platform's New Strategy in Media 2.0 Era - Based on “Keystone” concept & Google case [PDF]
The purpose of this paper is to suggest a new strategy of the platform in Media 2.0 era. This goal is approached by firstly examining conceptual change of the platform strategy from mass media world (Media 1.0) to micro media world (Media 2.0).
Song, Minzheong
core
Sino-African Philosophy: A Re-“Constructive Engagement” [PDF]
, 2019 “Constructive-Engagement” is a meta-philosophical and meta-methodological “strategy” suggested by Chinese and comparative philosophy scholar Bo Mou for analyzing and enriching philosophical exchange.
DOTTIN, Paul A.
core +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
How Green Branding Goal effects Technology Selection Strategy: Case Study of Tank Bioleaching technology selection [PDF]
مطالعات مدیریت توسعه سبزIntroductionThe world faces sustainability challenges in economic, environmental, and social dimensions. Unsustainable consumption and production are causing serious social and economic crises, threatening life on Earth.
Alireza Sheikh, Omid Esmaeili Shoja
doaj +1 more source
Demographic Variations in Achievement Goal Orientations among Prisoners on Formal and Vocational Training in Uganda [PDF]
, 2018 Educating Prisoners has become a worldwide concern as a measure that can save community costs associated with criminal behavior. In Uganda, there is low participation in formal and vocational training among prisoners which can be associated with lack of ...
Aheisibwe, Irene, Rukundo, Aloysius
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Goal-based Decision Strategies [PDF]
, 1991 We present a process model of decision making mediated by goals and relationships. The model is implemented in the V O T E computer program which simulates Congressional roll call voting. In this paper, we focus on VOTE's decision strategies, which are based on the need not only to arrive at a vote, but also to produce an explanation for each decision.
openaire