Results 71 to 80 of about 849,306 (267)

Improved indicators for the integrated assessment of coastal sustainable development based on Earth Observation Data

open access: yesInternational Journal of Digital Earth
Target 14 of the Sustainable Development Goals (SDG 14) depicts a better future regarding the capacity of coastal environments to cope with several developmental challenges.
Li Zhang   +8 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Large-Scale nighttime illuminated road extraction in the BTH region of China using SDGSAT-1 nighttime light data

open access: yesInternational Journal of Digital Earth
Nighttime illuminated roads (NTIRs) are closely related to residents' nighttime travel and activities. However, traditional nighttime light (NTL) data are not highly applicable for large-scale NTIR extraction tasks because of challenges such as low ...
Qiyuan Xie   +5 more
doaj   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

Changes in the Water Area of an Inland River Terminal Lake (Taitma Lake) Driven by Climate Change and Human Activities, 2017–2022

open access: yesRemote Sensing
Constructed from a dataset capturing the seasonal and annual water body distribution of the lower Qarqan River in the Taitma Lake area from 2017 to 2022, and combined with the meteorological and hydraulic engineering data, the spatial and temporal change
Feng Zi   +7 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle   +11 more
wiley   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda   +12 more
wiley   +1 more source

Individual Tree Crown Delineation Using Airborne LiDAR Data and Aerial Imagery in the Taiga–Tundra Ecotone

open access: yesRemote Sensing
The circumpolar Taiga–Tundra Ecotone significantly influences the feedback mechanism of global climate change. Achieving large-scale individual tree crown (ITC) extraction in the transition zone is crucial for estimating vegetation biomass in the ...
Yuanyuan Lin   +4 more
doaj   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan   +3 more
wiley   +1 more source

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