Results 51 to 60 of about 693,575 (310)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Goat (vol. 1, no. 4) 1969

, 1969
"The Goat" was an "underground" paper published by a group on the Springfield College campus. This radical newspaper was create by a student group Ad Hoc Committee for Student Self-Determination.
Ad Hoc Committee for Student Self Determination
core   +1 more source

On the angora goat

Papers and proceedings of the Royal Society of Tasmania, 1874
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Influence of Sheep Age at First Calving on the Productive Performance of Lambs from Tsigai breed

Scientific Papers Animal Science and Biotechnologies, 2023
The aim of this study was to determine the effects of age on reproductive indices and on growth performances, carcass and meat quality of Tsigai lambs coming from young females (8 months age), in order to improve meat quality and meat sensory ...
Elena Ilișiu, Andreea-Hortanse Anghel, Vasile-Călin Ilișiu, Camelia-Zoia Zamfir, Cristian-Vasile Ilișiu, Daniela-Rodica Mare, Dorina Nadolu, Ion-Dumitru Chirteș   +7 more
doaj  

The Goat (vol. 1, no. 1) 1968

, 1968
"The Goat" was an "underground" paper published by a group on the Springfield College campus. This radical newspaper was create by a student group Ad Hoc Committee for Student Self-Determination.
Ad Hoc Committee for Student Self-Determination
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Goat situation and research projects in Portugal [PDF]

, 2003
Portugal Goat Information In 2000 the goat population of Portugal was 623 000 heads, 162 000 less than in 1997 (785 000 heads) 188 000 less than 1995, confirming a downward trend since 1992 (862 000 heads). The dominant region is the Alentejo (South)
Teixeira, Alfredo
core   +1 more source

Effects of the concentration and nature of total dissolved solids in drinking water on feed intake, nutrient digestion, energy balance, methane emission, ruminal fermentation, and blood constituents in different breeds of young goats and hair sheep

Animal Nutrition
Understanding how different livestock species and breeds respond to consumption of brackish water could improve usage of this resource. Therefore, Angora, Boer, and Spanish goat doelings and Dorper, Katahdin, and St. Croix ewe lambs (6 animals per animal
Amlan Kumar Patra, Luana Paula dos Santos Ribeiro, Hirut Yirga, Adekayode O. Sonibare, Ahmed R. Askar, Ali H. Hussein, Ryszard Puchala, Arthur Louis Goetsch   +7 more
doaj   +1 more source