Results 61 to 70 of about 150 (115)

A GTPV-Based Murine Model Recapitulating Key Features of Lumpy Skin Disease for Preclinical Vaccine Evaluation

Animals
The global spread of lumpy skin disease (LSD), a devastating cattle disease caused by the lumpy skin disease virus (LSDV), is hampered by the lack of a practical small animal model for vaccine evaluation. Here, we established a mouse model by challenging
Wanfeng Ji, Xinjun Zhou, Sen Zhang, Xinwei Yuan, Wenying Wu, Xiaowen Xu, Aizhen Guo, Yingyu Chen   +7 more
doaj   +1 more source

Does Lumpy Skin Disease Have the Potential to Become Zoonotic?

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
Lauro Velazquez‐Salinas, Amanda M. Harvey, Chad Mire   +2 more
wiley   +1 more source

“FastCheck^FLI PPR-like”—A Molecular Tool for the Fast Genome Detection of PPRV and Differential Diagnostic Pathogens

Viruses, 2020
To assist the global eradication of peste des petits ruminants virus (PPRV), a molecular test for the rapid and reliable detection of PPRV was developed which additionally enables the detection of pathogens relevant for differential diagnostics. For this
Sabrina Halecker, Thomas C. Mettenleiter, Martin Beer, Bernd Hoffmann   +3 more
doaj   +1 more source

Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update

Virulence
Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across Asia and Europe in recent years. The LSD virus (LSDV) is a relatively poorly studied virus.
Naveen Kumar, Shalini Sharma, Bhupendra N. Tripathi   +2 more
doaj   +1 more source

Live attenuated goatpox vaccination in pregnant Murcia-Granada goats: dosage implications and outcomes

BMC Veterinary Research
Background Infectious diseases, particularly the Goatpox virus (GTPV) from the Poxviridae family, significantly impact livestock health and agricultural economies, especially in developing regions.
Hossein Esmaeili, Mohammadreza Ghorani, Seyed Mehdi Joghataei, Sergio Villanueva-Saz, Delia Lacasta   +4 more
doaj   +1 more source

Molecular Determinants of Species-Specific Interactions Between Protein Kinase R and Poxvirus K3 Orthologs

Viruses
Protein kinase R (PKR) is an antiviral protein that is involved in molecular “arms races” with viral antagonists. As a result, some PKR inhibitors, including the vaccinia virus (VACV) protein K3 and its orthologs from other poxviruses only inhibit PKRs ...
Chorong Park, Greg Brennan, Chen Peng, Chi Zhang, Jingxin Cao, Loubna Tazi, Stefan Rothenburg   +6 more
doaj   +1 more source

Emerging Goatpox Virus Threat in Wild Ruminants: First Documented Outbreak in the United Arab Emirates, 2024

Veterinary Sciences
The goatpox virus (GPV) is a highly contagious pathogen primarily affecting domestic small ruminants in endemic regions of Northern Africa, the Middle East, and Asia. This study reports the first confirmed outbreak of GPV in captive wild ruminants in the
Christiana Hebel, Ajith Kumar, Sunitha Joseph, Joerg Kinne, Nissy Annie Georgy Patteril, Florian Pfaff, Bernd Hoffmann, Rolf Schuster, Francois Le Grange, Ulrich Wernery   +9 more
doaj   +1 more source

In vitro antiviral activity of plant extracts on goatpox virus replication.

Indian journal of experimental biology, 2008
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all ...
V, Bhanuprakash, M, Hosamani, V, Balamurugan, P, Gandhale, Ram, Naresh, D, Swarup, R K, Singh   +6 more
openaire   +1 more source

Isolation, identification and phylogenetic analysis of a lumpy skin disease virus strain from diseased beef cattle in China

Animal Diseases
Lumpy skin disease (LSD) is a highly contagious viral disease in cattle caused by lumpy skin disease virus (LSDV), which belongs to the genus Capripoxvirus (CaPVs) within the family Poxviridae.
Xinwei Yuan, Xiaowen Xu, Qingni Li, Chen Wang, Zhijie Xiang, Yingyu Chen, Changmin Hu, Aizhen Guo   +7 more
doaj   +1 more source

Enhanced Recovery and Detection of Highly Infectious Animal Disease Viruses by Virus Capture Using Nanotrap^® Microbiome A Particles

Viruses
This study reports the use of Nanotrap® Microbiome A Particles (NMAPs) to capture and concentrate viruses from diluted suspensions to improve their recovery and sensitivity to detection by real-time PCR/RT-PCR (qPCR/RT-qPCR).
Amaresh Das, Joseph Gutkoska, Yadata Tadassa, Wei Jia   +3 more
doaj   +1 more source