Results 41 to 50 of about 392,022 (297)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Calcium and magnesium absorption and retention by growing goats offered diets with different calcium sources [PDF]

open access: yes, 2016
Calcium addition is necessary in order to balance the high phosphorus concentrations that are characteristic of high-concentrate ruminant diets. However, calcium sources differ in their bioavailability. Our objective was to determine apparent calcium and
Caldwell, James D.   +5 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Biotin fortification to sperm preparation medium enhances the motility and longevity by reducing lipid peroxidation in cryopreserved sperm

open access: yesIndian Journal of Animal Sciences, 2022
Biotin supplementation to the sperm cryopreservation medium appears to be beneficial in enhancing the in vitro sperm survival without affecting the fertilizing ability.
Ravi Ranjan   +5 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Mycobacterium avium subspecies paratuberculosis – an important food borne pathogen of high public health significance with special reference to India: an update

open access: yesVeterinary Quarterly, 2017
This review underlines the public health significance of ‘Indian Bison Type’ of Mycobacterium avium subspecies paratuberculosis (MAP) and also its potential as ‘zoonotic infection’. In the absence of control programs, bio-load of MAP is increasing and if
Kundan Kumar Chaubey   +8 more
doaj   +1 more source

Progesterone profile and ultrasonographic scanning of uterus during post partum period in Jakhrana goats

open access: yesIndian Journal of Animal Sciences, 2016
It is evident from our findings that oestrous cyclicity was not resumed during 60 days pp in Jakhrana female goats, as progesterone level remained at basal level (£ 1.00 ng/ml) during this period.
A K GOEL   +6 more
doaj   +1 more source

Changes in milk and plasma progesterone and pregnancy-associated glycoprotein and their relationships with the foetal number during early pregnancy in Jakhrana goats

open access: yesIndian Journal of Animal Sciences, 2021
This study was designed to investigate milk and circulating profiles of progesterone (P4) and pregnancy-associated glycoprotein (PAG) during early pregnancy and to determine their associations with the foetal numbers in Jakhrana goats.
N SHARMA, S P SINGH, A BHARADWAJ
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Development of real-time RT-PCR assay for diagnosis of viral enteritis in neonatal goat kids

open access: yesIndian Journal of Animal Sciences, 2020
Rotavirus gastroenteritis is a worldwide disease affecting primarily infants, young children and young ones of wide variety of mammalian and avian species.
SAPNA PRAJAPATI   +5 more
doaj   +1 more source

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