Results 71 to 80 of about 5,220,489 (200)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

open access: yesHistopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty   +7 more
wiley   +1 more source

Cytological features of signet‐ring cell carcinoma of the lung: Comparison with the goblet‐cell‐type adenocarcinoma of the lung

open access: yesDiagnostic Cytopathology, 2009
AbstractSignet‐ring cell carcinoma (SRCC) and goblet‐cell‐type adenocarcinoma (GCA) are mucin‐producing lung adenocarcinomas. Primary SRCC shows an aggressive clinical course, whereas GCA shows infrequent distant metastasis, but more frequent intrapulmonary metastases resembling lobar pneumonia. To distinguish SRCC from GCA, this study investigated the
Koji, Tsuta   +7 more
openaire   +3 more sources

Appearances Can Be Deceiving: A Case Report of Asymptomatic Appendiceal Goblet Cell Adenocarcinoma Presenting as an Ovarian Tumor

open access: yesCase Reports in Oncology
Introduction: Goblet cell adenocarcinoma (GCA) of the appendix is an uncommon type of cancer that includes both epithelial and neuroendocrine features, with goblet cells present.
Hiroko Fukasawa   +8 more
doaj   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon   +6 more
wiley   +1 more source

Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes [PDF]

open access: yes, 2007
Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process.
Jones, Jon   +15 more
core   +1 more source

MOLECULAR MARKERS OF MUCOSA HARBORING GASTRIC ADENOMAS

open access: yesArquivos de Gastroenterologia, 2013
Context Gastric adenoma is a precursor lesion of the adenocarcinoma. Objective To characterize gastric adenomas according to the mucin immunoexpression and to evaluate the immunoexpression of p53, p16ink4a, BCL-2, cyclin D, Ki-67, in the adenoma and in
Adriana Vaz SAFATLE-RIBEIRO   +5 more
doaj   +1 more source

Clinical outcome with surgical excision of jejunal adenocarcinoma in a 10‐year‐old Vietnamese pot‐bellied pig

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A Vietnamese pot‐bellied pig was assessed for a 1‐week history of anorexia and at least 1 week of no defecation. Contrast‐enhanced abdominal computed tomography revealed a focal intestinal stricture with secondary chronic partial mechanical obstruction. Exploratory laparotomy revealed a 5‐cm mass incorporating the distal jejunum.
Julia A. Horton   +3 more
wiley   +1 more source

Colonic anaplastic soft tissue sarcoma in a western hognose snake (Heterodon nasicus)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Neoplastic disease is increasingly being recognized in snakes as a cause of morbidity, with gastrointestinal neoplasms being commonly reported. However, clinical signs are often non‐specific making diagnosis challenging. This case describes the first report of a colonic anaplastic soft tissue sarcoma in a western hognose snake (Heterodon ...
Colin Clarke   +4 more
wiley   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

open access: yesJournal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer   +9 more
wiley   +1 more source

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