Results 81 to 90 of about 4,473,643 (292)

Functional biology of intestinal goblet cells

open access: yes, 1991
Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins.
R. D. Specian, M. G. Oliver
core   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Clinical and Molecular Analyses of Intestinal Goblet Cell Acidomucins and Cysteine Metabolism [PDF]

open access: yes, 2010
Goblet cells are key contributors to intestinal mucosal barrier function through their role in production of mucins and other important secretory products, which include trefoil factor 3 (TFF3) and resistin like molecule β (RETNLB).
Croix, Jennifer A.
core  

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

open access: yesAdvanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang   +7 more
wiley   +1 more source

Autoimmune Enteropathy with Goblet-Cell Antibodies [PDF]

open access: yesJournal of the Royal Society of Medicine, 1999
Boari flap was undertaken, and histological examination confirmed the presence of a single pTaG 1 papillary transitional cell carcinoma in the lower third of the ureter. Subsequent cystoscopies at three and six months were normal. One year after the surgical procedure the patient developed painless haematuria.
D, Rogahn, C P, Smith, A, Thomas
openaire   +2 more sources

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

open access: yesAdvanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

MORPHOLOGICAL STUDIES ON THE GUTTURAL POUCH OF DONKEY 1 - THE LINING EPITHELIUM [PDF]

open access: yesAssiut Veterinary Medical Journal, 1994
The ep < /strong>ithelium of the guttural p < /strong>ouch of the donkey has been studied at the ultrastructural level. It was found to be a typical pseudostratified ciliated columnar ep < /strong>ithelium formed of basal, intermediate,
A.O. SALEM   +2 more
doaj   +1 more source

Secretagogue response of goblet cells and columnar cells in human colonic crypts1

open access: yes, 2000
Crypts of Lieberkühn were isolated from human colon, and differential interference contrast microscopy distinguished goblet and columnar cells.
Susan Troutman Halm, Dan R. Halm
core   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]

open access: yes, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T.   +12 more
core   +2 more sources

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

open access: yesAdvanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang   +12 more
wiley   +1 more source

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