Results 71 to 80 of about 91,974 (203)

Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments. [PDF]

PLoS ONE, 2017
PURPOSE:Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under ...
Céline Portal, Valérie Gouyer, Frédéric Gottrand, Jean-Luc Desseyn   +3 more
doaj   +1 more source

Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. [PDF]

PLoS ONE, 2014
Dysfunction of Paneth and goblet cells in the intestine contributes to inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC).
Giuseppe Lo Sasso, Dongryeol Ryu, Laurent Mouchiroud, Samodha C Fernando, Christopher L Anderson, Elena Katsyuba, Alessandra Piersigilli, Michael O Hottiger, Kristina Schoonjans, Johan Auwerx   +9 more
doaj   +1 more source

Obesity and Asthma: Adiponectin Receptor 1 (Adipo R1) and Adiponectin Receptor 2 (Adipo R2) are expressed by normal human bronchial epithelial (NHBE) cells at air-liquid interface (ALI) and expression changes with IL-13 stimulation [PDF]

, 2016
Obesity is recognized as an important risk factor for the development of many chronic diseases such as hypertension, Type 2 diabetes mellitus (T2DM) cardiovascular disease, cancer, renal disease, neurologic dysfunction, metabolic syndrome and asthma (3 ...
Bradley, Jennifer L
core   +1 more source

The host immune response to gastrointestinal nematode infection in sheep [PDF]

, 2015
non peer reviewedGastrointestinal nematode infection represents a major threat to the health, welfare and productivity of sheep populations worldwide. Infected lambs have a reduced ability to absorb nutrients from the gastrointestinal tract, resulting in
Abraham, Ahmed, Akiho, Amarante, Andronicos, Anthony, Balic, Balic, Balic, Balic, Becattini, Beraldi, Bishop, Bisset, Bisset, Bowdridge, Brunsdon, Brunsdon, Brunsdon, Buddle, Cardia, Clarke, Conway, Coop, Craig, Craig, Crespo, Dawicki, Deplancke, deSchoolmeester, Diez-Tascon, Donaldson, Douch, Douch, Dunsmore, Else, Finkelman, Finkelman, Finney, French, Fuhrman, Geijtenbeek, Gilfillan, Gill, Glass, Gossner, Gossner, Grainger, Halliday, Hansen, Harriman, Harrison, Harrison, Hassan, Hassan, Henderson, Hogan, Houdijk, Hsieh, Huntley, Huntley, Huntley, Ingham, Khan, Kim, Kooyman, Korn, Lacroux, Lazarevic, Lighvani, MacKinnon, Madden, Malan, Mantovani, Marson, McClure, McGuckin, McKenna, McRae, McSorley, Meeusen, Mori, Nair, Ohkura, Paul, Pernthaner, Pernthaner, Pettit, Rainbird, Rosenberg, Sangster, Scott, Seaton, Shakya, Shaw, Shaw, Smith, Smith, Stear, Stear, Stear, Stear, Stevenson, Stone, Strain, Sutherland, Szabo, Taylor, Terefe, Urb, Vallance, Vignali, Voehringer, Williams   +113 more
core   +1 more source

A Model of Colonic Crypts using SBML Spatial

, 2013
The Spatial Processes package enables an explicit definition of a spatial environment on top of the normal dynamic modeling SBML capabilities. The possibility of an explicit representation of spatial dynamics increases the representation power of SBML ...
Antoniotti, Marco, Maj, Carlo, Ramazzotti, Daniele   +2 more
core   +2 more sources

Evaluation of a microbial muramidase supplementation on growth performance, apparent ileal digestibility, and intestinal histology of broiler chickens [PDF]

, 2019
The current study evaluated the effects of different inclusion levels of microbial muramidase (Muramidase 007, DSM Nutritional Products) on gastrointestinal functionality by determination of apparent ileal digestibility (AID) of nutrients, investigation ...
Goodarzi Boroojeni, F., Männer, K., Pérez Calvo, E., Rieger, J., Zentek, J.   +4 more
core   +1 more source

Age-related decline in goblet cell numbers and mucin content of the human colon: Implications for lower bowel functions in the elderly

Experimental and Molecular Pathology
Background & aims: Older people experience a greater incidence of lower bowel disorders, including constipation. Causes can include factors associated with growing older, such as use of medications or disease, but compounded by degenerative changes ...
Nicholas Baidoo, Gareth J. Sanger
doaj   +1 more source

Zebrafish Agr2 is required for terminal differentiation of intestinal goblet cells.

PLoS ONE, 2012
BackgroundMammalian Anterior Gradient 2 (AGR2) is a protein disulfide isomerase that is required for the production of intestinal mucus and Paneth and goblet cell homeostasis. However, whether increased endoplasmic reticulum (ER) stress occurs in Agr2(-/-
Yi-Chung Chen, Yu-Fen Lu, I-Chen Li, Sheng-Ping L Hwang   +3 more
doaj   +1 more source

Light microscopic study on the absorptive cells and goblet cells in the intestine of adult common carp Cyprinus carpio

The Iraqi Journal of Veterinary Medicine, 2019
The purpose of this study was to describe of some histological structures and histochemical features of the absorptive cells and goblet cells in intestine of common carp. In this study, Fifteen adult male common carp were catching alive from the AL-Forat
Khalid Hadi Kadhim
doaj   +1 more source

Connexin communication compartments and wound repair in epithelial tissue [PDF]

, 2018
Epithelial tissues line the lumen of tracts and ducts connecting to the external environment. They are critical in forming an interface between the internal and external environment and, following assault from environmental factors and pathogens, they ...
Chanson, Marc, Martin, Patricia E., O'Shaughnessy, Erin M., Watanabe, Masakatsu, Zoso, Alice   +4 more
core   +4 more sources