Results 51 to 60 of about 4,055,799 (309)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Endometriosis presenting as a rectal stricture in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report

Frontiers in Gastroenterology
Patients with ulcerative colitis (UC) are at an increased risk of colorectal cancer (CRC), which is compounded in the presence of other risk factors such as primary sclerosing cholangitis (PSC) and stricture.
Daniel Chorley, Ibrahim Mian, Deloshaan Subhaharan, Deloshaan Subhaharan, Pradeep Kakkadasam Ramaswamy   +4 more
doaj   +1 more source

Towards a Unified Theory of the Law of Employment Discrimination [PDF]

, 2001
TowardsaUnifiedTheoryoftheLawEmployment.pdf: 988 downloads, before Oct.
Gold, Michael Evan
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Hybrid gold single crystals incorporating amino acids

, 2016
Composite hybrid gold crystals are of profound interest in various research areas ranging from materials science to biology. Their importance is due to their unique properties and potential implementation, for example in sensing or in bio-nanomedicine ...
Chen, Linfeng, Fitch, Andy N, Pokroy, Boaz, Polishchuk, Iryna, Weber, Eva   +4 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Spontaneous splenic rupture associated with Q fever and portal hypertension: A case report

Frontiers in Medicine
Spontaneous splenic rupture (SSR) is an exceptionally rare and life-threatening condition, with its pathophysiology remaining poorly understood. This report describes the first documented case of SSR in a patient with Q fever infection and underlying ...
Cecil Mustafiz, Cecil Mustafiz, Deloshaan Subhaharan, Deloshaan Subhaharan, Daniel Chorley, Tariq Masood   +5 more
doaj   +1 more source

Towards Embedded Electrochemical Sensors for On-Site Nitrite Detection by Gold Nanoparticles Modified Screen Printed Carbon Electrodes [PDF]

, 2023
Anurag Adiraju, Rohan Munjal, Christian Viehweger, Ammar Al‐Hamry, Amina Brahem, Jawaid Hussain, Sanhith Kommisetty, Aditya Jalasutram, Christoph Tegenkamp, Olfa Kanoun   +9 more
openalex   +1 more source

Employment Discrimination and the Assumption of Equality [PDF]

, 1994
The assumption of equality undergirds the American law of employment discrimination. The assumption is that racial and sexual classes are equally qualified for jobs.
Gold, Michael Evan
core   +1 more source

Strengthening gold-gold bonds by complexing gold clusters with noble gases

, 2015
We report an unexpectedly strong and complex chemical bonding of rare-gas atoms to neutral gold clusters. The bonding features are consistently reproduced at different levels of approximation within density-functional theory and beyond: from GGA, through
Ghiringhelli, Luca M., Levchenko, Sergey V.   +1 more
core   +1 more source