Results 1 to 10 of about 2,773,224 (190)

When the Hoofbeats Are Zebras

open access: yesAnnals of Internal Medicine: Clinical Cases, 2022
Nearly 2 decades into the genomic era, individuals with mendelian disorders, which are conditions caused by pathogenic variation in a single gene, have experienced improved health outcomes and life expectancy. Clinicians must be able to identify and care
Jessica I. Gold
doaj   +1 more source

Context-dependent relationships between locus coeruleus firing patterns and coordinated neural activity in the anterior cingulate cortex

open access: yeseLife, 2022
Ascending neuromodulatory projections from the locus coeruleus (LC) affect cortical neural networks via the release of norepinephrine (NE). However, the exact nature of these neuromodulatory effects on neural activity patterns in vivo is not well ...
Siddhartha Joshi, Joshua I Gold
doaj   +1 more source

Biological Activity of Gold Compounds against Viruses and Parasitosis: A Systematic Review

open access: yesBioChem, 2022
In this contribution, we provide an overview of gold compound applications against viruses or parasites during recent years. The special properties of gold have been the subject of intense investigation in recent years, which has led to the development ...
Custódia Fonseca, Manuel Aureliano
doaj   +1 more source

KINETIC ALGORITHMS FOR HARBOUR MANAGEMENT [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Modern harbour management for a busy port needs to resolve a variety of simultaneous problems. Harbour traffic may be busy and the waterways congested, both by the major shipping and by the attendant harbour tugs.
C. M. Gold   +3 more
doaj   +1 more source

Contraceptive use in women with inherited metabolic disorders: a retrospective study and literature review

open access: yesOrphanet Journal of Rare Diseases, 2022
Background Reproductive planning is an emerging concern for women with inherited metabolic disease (IMD). Anticipatory guidance on contraception is necessary to prevent unintended pregnancies in this population.
Jessica I. Gold   +3 more
doaj   +1 more source

(Z)-5-Benzylidene-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole

open access: yesMolbank, 2023
By strategic use of the valence difference between hard gold(III) and soft gold(I) catalysts, one-pot synthesis of (Z)-5-benzylidene-4-phenyl-2-(p-tolyl)-4,5-dihydrooxazole (15) from propargylic alcohol (9) and p-toluamide (13) was achieved via gold(III)-
Nobuyoshi Morita   +5 more
doaj   +1 more source

A healthy fear of the unknown: perspectives on the interpretation of parameter fits from computational models in neuroscience. [PDF]

open access: yesPLoS Computational Biology, 2013
Fitting models to behavior is commonly used to infer the latent computational factors responsible for generating behavior. However, the complexity of many behaviors can handicap the interpretation of such models.
Matthew R Nassar, Joshua I Gold
doaj   +1 more source

Gold/Pentablock Terpolymer Hybrid Multifunctional Nanocarriers for Controlled Delivery of Tamoxifen: Effect of Nanostructure on Release Kinetics

open access: yesMolecules, 2022
Here, we describe the preparation and characterization of organic/inorganic hybrid polymer multifunctional nanocarriers. Novel nanocomposites of gold nanoparticles using pH-responsive coordination pentablock terpolymers of poly(ε-caprolactone)-b-poly ...
Maria-Teodora Popescu   +1 more
doaj   +1 more source

Small Gold(I) and Gold(I)–Silver(I) Clusters by C−Si Auration [PDF]

open access: yesChemistry – A European Journal, 2020
AbstractAuration of o‐trimethylsilyl arylphosphines leads to the formation of gold and gold–silver clusters with ortho‐metalated phosphines displaying 3c–2e Au−C−M bonds (M=Au/Ag). Hexagold clusters [Au6L4](X)2 are obtained by reaction of (L−TMS)AuCl with AgX, whereas reaction with AgX and Ag2O leads to gold–silver clusters [Au4Ag2L4](X)2.
Xiao‐Li Pei   +3 more
openaire   +3 more sources

Gold Nanoparticle-Based Resuscitation of Cefoxitin against Clinical Pathogens: A Nano-Antibiotic Strategy to Overcome Resistance

open access: yesNanomaterials, 2022
Gold nanoparticles have gained popularity as an effective drug delivery vehicle due to their unique features. In fact, antibiotics transported via gold nanoparticles have significantly enhanced their potency in the recent past.
Ahmed Alafnan   +8 more
doaj   +1 more source

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