Results 1 to 10 of about 62,754 (156)

Organometallic gold(I) and gold(III) complexes for lung cancer treatment [PDF]

Frontiers in Pharmacology, 2022
Metal compounds, especially gold complexes, have recently gained increasing attention as possible lung cancer therapeutics. Some gold complexes display not only excellent activity in cisplatin-sensitive lung cancer but also in cisplatin-resistant lung ...
Juzheng Zhang, Yanping Li, Ronghao Fang, Wei Wei, Yong Wang, Jiamin Jin, Feng Yang, Jian Chen   +7 more
doaj   +4 more sources

Gold(III) Complexes Activity against Multidrug-Resistant Bacteria of Veterinary Significance [PDF]

Antibiotics, 2022
The emergence and spread of multidrug-resistant bacteria are a global concern. The lack of new antibiotics in the pipeline points to the need for developing new strategies. In this sense, gold(III) complexes (G3Cs) could be a promising alternative due to
Carlos Ratia, Sara Sueiro, Raquel G. Soengas, María José Iglesias, Fernando López-Ortiz, Sara María Soto   +5 more
doaj   +4 more sources

Steric and Electronic Effects in N-Heterocyclic Carbene Gold(III) Complexes: An Experimental and Computational Study [PDF]

Molecules, 2022
A series of neutral acridine-based gold(III)-NHC complexes containing the pentafluorophenyl (–C6F5) group were synthesized. All of the complexes were fully characterized by analytical techniques.
Miguel A. Rosero-Mafla, Jhon Zapata-Rivera, M. Concepción Gimeno, Renso Visbal   +3 more
doaj   +2 more sources

Gold(III) Complexes: An Overview on Their Kinetics, Interactions With DNA/BSA, Cytotoxic Activity, and Computational Calculations [PDF]

Frontiers in Chemistry, 2020
In the last few years, metallodrugs play a key role in the development of medicinal chemistry. The choice of metal ion, its oxidation state and stability, and the choice of inert and labile ligands are just some of the very important facts which must be ...
Snežana Radisavljević, Biljana Petrović   +1 more
doaj   +2 more sources

Synthesis and Structural Characterization of Phosphanide Gold(III)/Gold(I) Complexes and Their Thallium(III) and Gold(III) Precursors

Molecules, 2023
In this paper, we describe a series of diphenylphosphane and diphenylphosphanide gold(III) and gold(III)/gold(I) complexes containing 3,5-C6Cl2F3 as aryl ligands at gold that have been synthesized due to the arylating and oxidant properties of the new ...
Laura Coconubo-Guio, José M. López-de-Luzuriaga, Sonia Moreno, M. Elena Olmos   +3 more
doaj   +5 more sources

Synthesis of Cyclometalated Gold(III) Complexes via Catalytic Rhodium to Gold(III) Transmetalation

Angewandte Chemie - International Edition, 2022
Abstract A catalytic method to synthesize a broad array of cyclometalated (C^N)gold(III) complexes is reported here. An unprecedented Rh‐to‐Au III transmetalation allows the facile transfer of (C^N) ligands between these two metals in a redox‐neutral process.
Cristina Nevado, Alexandre Genoux, Enrique Gomez Bengoa   +2 more
exaly   +6 more sources

The trans-influence in gold chemistry from a catalytic perspective [PDF]

Beilstein Journal of Organic Chemistry
Gold catalysis has developed into an increasingly important method in organic synthesis. Especially the potential of gold(I,III) redox systems and gold(III) complexes has more recently become a focus of interest.
Manfred Bochmann
doaj   +2 more sources

Gold(i) and gold(iii) complexes of triazolyl-functionalised NHCs. [PDF]

RSC Adv
Au I /Au III complexes of triazolyl functionalized imidazolium salts were synthesised. Au I complexes reacted with SOCl 2 to form Au III
Al-Buthabhak HS, Al-Ameed K, Yu Y, Sobolev AN, Moggach SA, Al-Salami H, Ferro V, Baker MV.   +7 more
europepmc   +5 more sources

Gold(I) and Gold(III) Complexes of Cyclic (Alkyl)(amino)carbenes. [PDF]

Organometallics, 2015
The chemistry of Au(I) complexes with two types of cyclic (alkyl)(amino)carbene (CAAC) ligands has been explored, using the sterically less demanding dimethyl derivative Me2CAAC and the 2-adamantyl ligand AdCAAC. The conversion of (AdCAAC)AuCl into (AdCAAC)AuOH by treatment with KOH is significantly accelerated by the addition of tBuOH. (AdCAAC)AuOH is
Romanov AS, Bochmann M.
europepmc   +5 more sources

Heteroleptic (S^C)-cyclometallated gold(III) complexes as novel antiviral agents [PDF]

Heliyon
Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in healthy individuals and the associated high morbidity in immunosuppressed patients, particularly among the paediatric population, a specific treatment for this virus ...
María Balsera-Manzanero, Raquel G. Soengas, Marta Carretero-Ledesma, Carlos Ratia, M. José Iglesias, Jerónimo Pachón, Fernando López-Ortiz, Elisa Cordero, Sara M. Soto, Javier Sánchez-Céspedes   +9 more
doaj   +2 more sources