Results 101 to 110 of about 1,037,208 (379)

Chlamydial infection from outside to inside [PDF]

, 2019
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke, Sanders, Niek, Vanrompay, Daisy   +2 more
core   +2 more sources

Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer.

Cancer Research, 2014
Downregulation of cell-cell adhesion and upregulation of cell migration play critical roles in the conversion of benign tumors to aggressive invasive cancers.
E. Tokuda, T. Itoh, Junya Hasegawa, T. Ijuin, Y. Takeuchi, Y. Irino, Miki Fukumoto, T. Takenawa   +7 more
semanticscholar   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

The Golgin Family of Coiled-Coil Tethering Proteins

Frontiers in Cell and Developmental Biology, 2016
The golgins are a family of predominantly coiled-coil proteins that are localized to the Golgi apparatus. Golgins are present in all eukaryotes, suggesting an evolutionary conserved function.
Tomasz M Witkos, Martin eLowe
doaj   +1 more source

Urothelial plaque formation in post-Golgi compartments. [PDF]

PLoS ONE, 2011
Urothelial plaques are specialized membrane domains in urothelial superficial (umbrella) cells, composed of highly ordered uroplakin particles. We investigated membrane compartments involved in the formation of urothelial plaques in mouse umbrella cells.
Samo Hudoklin, Kristijan Jezernik, Josef Neumüller, Margit Pavelka, Rok Romih   +4 more
doaj   +1 more source

Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ-Secretase Activity

mBio, 2014
The route taken by papillomaviruses from the cell surface to the nucleus during infection is incompletely understood. Here, we developed a novel human papillomavirus 16 (HPV16) pseudovirus in which the carboxy terminus of the minor capsid protein L2 is ...
Wei Zhang, Teymur Kazakov, A. Popa, D. DiMaio   +3 more
semanticscholar   +1 more source

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

Advanced Science, EarlyView.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu, Xin‐Yu Zhang, Xin‐Yu Ma, Yue‐Yue Wei, Lei‐Lei Wang, Ze‐Bang Du, Xiao‐Gang Xia, Lin Che, Dong‐Bei Guo, Han‐Ying Zheng, You‐Liang Yao, Wen‐Gang Li, Yu‐Chun Lin, Zhong‐Ning Lin   +13 more
wiley   +1 more source

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network [PDF]

, 2008
The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion ...
Aghi, Baeuerle, Beisswanger, Bonifacino, Daniel C. Smith, David J. Stephens, Donaldson, Endo, Falguieres, Feng, Feng, Fjeldstad, Frédéric Boal, Fujinaga, Gallione, Garred, Girod, Guy J. Clarkson, Hallas, Helms, Huttner, J. Michael Lord, Johannes, Jones, Joseph, Kovbasnjuk, Lee, Lippincott-Schwartz, Lippincott-Schwartz, Ludger Johannes, Lynne M. Roberts, Mohammed Amessou, Mossessova, Muller, Nichols, Orci, Ouyang, Peter Watson, Peyroche, Ponnambalam, Prescott, Presley, Ram, Ram, Reaves, Reaves, Robba, Robert A. Spooner, Robineau, Sandvig, Sandvig, Scheel, Schekman, Shima, Shvedov, Smith, Spooner, Stephens, Thyberg, Watson, White, Wood, Zeeh, Zeghouf   +63 more
core   +5 more sources

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Ouabain-induced cytoplasmic vesicles and their role in cell volume maintenance [PDF]

, 2015
Cellular swelling is controlled by an active mechanism of cell volume regulation driven by a Na+/K+-dependent ATPase and by aquaporins which translocate water along the osmotic gradient. Na+/K+-pump may be blocked by ouabain, a digitalic derivative, by
MORGANTE, Emanuela, Rossum, G. D. Van, Russo, A., RUSSO, Matteo Antonio, TAFANI, MARCO   +4 more
core   +1 more source