Results 121 to 130 of about 85,181 (295)
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Biotechnology and Bioengineering, EarlyView.Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Targeting and fusion proteins during mammalian spermiogenesis
Biological Research, 2001 Regulated exocytosis is controlled by internal and external signals. The molecular machinery controlling the sorting from the newly synthesized vesicles from the Golgi apparatus to the plasma membrane play a key role in the regulation of both the number ...
JOÃO RAMALHO-SANTOS, RICARDO D. MORENO
doaj
The Golgi apparatus: going round in circles?
, 2002 Recent studies have questioned the idea that the Golgi complex is a stable organelle with a unique identity through which secretory cargo is transported by vesicles.
Barr, F. A., Francis A Barr
core +1 more source
BMEMat, EarlyView.A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie +12 more
wiley +1 more source
AFM images of Golgi apparatus.
, 2013 (A) AFM image of a stack of membranous cisternae. Scale bar is 1 µm. (B) Magnification of the green square area in (A). (C) Cross-section analysis along the green line drawn in (B). (D) AFM image of tubule network of Golgi apparatus.
Weiheng Su (402758) +5 more
core +1 more source
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
BMEMat, EarlyView.This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Ca2+ signalling in the Golgi apparatus
, 2011 The Golgi apparatus plays a central role in lipid and protein post-translational modification and sorting. Morphologically the organelle is heterogeneous and it is possible to distinguish stacks of flat cysternae (cis- and medial Golgi), tubular ...
CAPITANIO, PAOLA +3 more
core +1 more source
BMEMat, EarlyView.A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao +9 more
wiley +1 more source
SRC recruits CBLC to the Golgi apparatus.
, 2015 (A) CBL and CBLC localize to the Golgi apparatus. MannII-GFP and endogenous CBL, CBLB, or CBLC staining in HeLa cells. (B) SRC activation enhances recruitment of CBLC to the Golgi apparatus.
Adrian Boey (573783) +5 more
core +1 more source