Results 131 to 140 of about 956,222 (367)
We describe a green fluorescent protein (GFP)–based assay for investigating membrane traffic on the secretory pathway in plants. Expression of AtRab1b(N121I), predicted to be a dominant inhibitory mutant of the Arabidopsis Rab GTPase AtRab1b, resulted in
H. Batoko+3 more
semanticscholar +1 more source
Fluorescence Lifetime Multiplexing with Environment‐Sensitive Chemigenetic Probes
HaloTag (HT) is a versatile self‐labeling protein that has been widely adopted in fluorescence microscopy. Besides its established use as an intensity‐based marker and sensor, interest in using HT for multiplexed fluorescence lifetime imaging microscopy (FLIM) has recently arisen.
Sarah Emmert+2 more
wiley +1 more source
Golgi apparatus and golgi zone
The author of this paper has attempted to clarify some problems concerning the nomenclature of Golgi apparatus and Golgi zone. The actual aim of this paper is to summarize — while using the more safe nomenclature—the existing knowledge about the functional relations between nucleus and cytoplasm arising from the study of the juxtanuclear zone by ...
openaire +2 more sources
The Menkes P‐type ATPase (MNK), encoded by the Menkes gene (MNK; ATP7A), is a transmembrane copper‐translocating pump which is defective in the human disorder of copper metabolism, Menkes disease.
M. Petris+5 more
semanticscholar +1 more source
First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger+7 more
wiley +1 more source
Subcellular localization of microsomal triglyceride transfer protein
Microsomal triglyceride transfer protein (MTP) is essential for the assembly of apolipoprotein B-containing lipoproteins. Within the endoplasmic reticulum, it transfers lipid from the membrane to the forming lipoprotein.
Larry L. Swift+8 more
doaj
It is well‐established that tailoring the structural properties of nanoparticles, e.g., their size, shape, available active surface and interaction with metal oxide supports, imparts significant control on catalytic transformations. However, this often relies on the use of stabilizing (capping) agents.
George F. Tierney+8 more
wiley +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Brain endothelial cells (BECs), denoting the blood–brain barrier (BBB), can be specifically transduced both in vitro and in vivo following intravenous administration of the AAV‐BR1 vector, which onsets the synthesis of recombinant NPC2 protein from the BECs.
Charlotte Laurfelt Munch Rasmussen+8 more
wiley +1 more source
The Cerebellum: New Computational Model that Reveals its Primary Function to Calculate Multibody Dynamics Conform to Lagrange-Euler Formulation [PDF]
Cerebellum is part of the brain that occupies only 10% of the brain volume, but it contains about 80% of total number of brain neurons. New cerebellar function model is developed that sets cerebellar circuits in context of multibody dynamics model computations, as important step in controlling balance and movement coordination, functions performed by ...
arxiv