Results 141 to 150 of about 956,222 (367)

Localization of proteins to the Golgi apparatus

open access: yesTrends in Cell Biology, 1998
For the Golgi apparatus to perform its various unique roles it must maintain a population of resident proteins. These residents include the enzymes that modify the proteins and lipids passing through the Golgi, as well as the proteins involved in vesicle formation and protein sorting.
openaire   +3 more sources

The golgin coiled-coil proteins of the Golgi apparatus.

open access: yesCold Spring Harbor Perspectives in Biology, 2011
A number of long coiled-coil proteins are present on the Golgi. Often referred to as "golgins," they are well conserved in evolution and at least five are likely to have been present in the last common ancestor of all eukaryotes.
S. Munro
semanticscholar   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Nonequilibrium mechanisms underlying de novo biogenesis of Golgi cisternae [PDF]

open access: yesarXiv, 2016
A central issue in cell biology is the physico-chemical basis of organelle biogenesis in intracellular trafficking pathways, its most impressive manifestation being the biogenesis of Golgi cisternae. At a basic level, such morphologically and chemically distinct compartments should arise from an interplay between the molecular transport and chemical ...
arxiv  

Nucleosidediphosphatase activity in the Golgi apparatus and its usefulness for cytological studies.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1961
cytidine, and adenosine; thiamine pyrophosphate (Sigma); riboflavin phosphate (Sigma); and inorganic pyrophosphate (Merck). The last of these compounds was tested in the system of Naidoo and Pratt,"' with manganese substituted for magnesium ions ...
A. B. Novikoff, S. Goldfischer
semanticscholar   +1 more source

Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles

open access: yesExploration, EarlyView.
This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley   +1 more source

Active morphodynamics of intracellular organelles in the trafficking pathway [PDF]

open access: yesarXiv
From the Golgi apparatus to endosomes, organelles in the endomembrane system exhibit complex and varied morphologies that are often related to their function. Such membrane-bound organelles operate far from equilibrium due to directed fluxes of smaller trafficking vesicles; the physical principles governing the emergence and maintenance of these ...
arxiv  

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