Results 141 to 150 of about 1,037,208 (379)

Seamlessly Overcoming Biological Barriers with a Small Photosensitizer to Treat Metastatic Tumors with Photodynamic Therapy

open access: yesAngewandte Chemie, EarlyView.
LUZ 51 is a relatively small and amphiphilic photosensitizer that accumulates in poorly‐vascularized tumors, is rapidly internalized by cancer cells, does not elicit skin photosensitivity and triggers robust immunological responses that reduce spontaneous metastasis.
Mafalda Penetra   +7 more
wiley   +2 more sources

Targeting and fusion proteins during mammalian spermiogenesis

open access: yesBiological Research, 2001
Regulated exocytosis is controlled by internal and external signals. The molecular machinery controlling the sorting from the newly synthesized vesicles from the Golgi apparatus to the plasma membrane play a key role in the regulation of both the number ...
JOÃO RAMALHO-SANTOS, RICARDO D. MORENO
doaj  

Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis

open access: yesAdvanced Science, EarlyView.
Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv   +7 more
wiley   +1 more source

Transient domain formation in membrane-bound organelles undergoing maturation

open access: yes, 2013
The membrane components of cellular organelles have been shown to segregate into domains as the result of biochemical maturation. We propose that the dynamical competition between maturation and lateral segregation of membrane components regulates domain
Dmitrieff, Serge, Sens, Pierre
core   +3 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Endomannosidase undergoes phosphorylation in the Golgi apparatus [PDF]

open access: yes, 2017
Glucose residues from N-linked oligosaccharides are removed by glucosidases I and II in the endoplasmic reticulum (ER) or by the alternate endomannosidase pathway in the Golgi apparatus.
Guhl, Bruno   +3 more
core  

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang   +11 more
wiley   +1 more source

A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation

open access: yesAdvanced Science, EarlyView.
We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong   +4 more
wiley   +1 more source

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