Results 181 to 190 of about 1,085,148 (332)

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Understanding brain calcification via N-terminal acetylation at the Golgi apparatus. [PDF]

Brain
Siggervåg A, Bekkelund ÅK, Saraste J, Aksnes H.   +3 more
europepmc   +1 more source

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

Science Signaling, 2015
Zhaokang Yang, Hannah M. Kirton, David A. MacDougall, J. Boyle, J. Deuchars, B. Frater, S. Ponnambalam, Matthew E. L. Hardy, E. White, S. Calaghan, C. Peers, D. Steele   +11 more
semanticscholar   +1 more source

Alphafuser: a parsimonious approach to predicting higher‐order protein complexes

Acta Crystallographica Section D, EarlyView.
Alphafuser is a structure‐prediction pipeline that integrates experimental interaction data with AlphaFold‐based modeling to systematically assemble multiprotein complexes in a computationally efficient manner. By implementing an ipTM‐based pruning algorithm and validating against known structures and experimental assays, Alphafuser enables the ...
Audrey Guillotin, Stephanie Hutin, Lorelei Masselot-Joubert, Kamel Hammani, Chloe Zubieta, Max Nanao   +5 more
wiley   +1 more source

Stacks on tracks: the plant Golgi apparatus traffics on an actin/ER network.

The Plant Journal, 1998
P. Boevink, K. Oparka, S. S. Cruz, B. Martin, A. Betteridge, C. Hawes   +5 more
semanticscholar   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

Editorial: Golgi Dynamics in Physiological and Pathological Conditions

Frontiers in Cell and Developmental Biology, 2020
Kristian Prydz, Vladimir Lupashin, Yanzhuang Wang, Jaakko Saraste   +3 more
doaj   +1 more source

Small-molecule probes for imaging and impairing the Golgi apparatus in cancer. [PDF]

RSC Med Chem
Kumar P, Sengupta P, Basu S.
europepmc   +1 more source

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation [PDF]

, 2014
Andersen, MR, Fan, Y, Jimenez del Val, I, Kontoravdi, C, Muller, C, Rasmussen, SK, Sen, JW, Weilguny, D   +7 more
core   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source