Results 211 to 220 of about 1,085,148 (332)

The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation

The FEBS Journal, EarlyView.
The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak, In‐Ja L. Byeon, Ryan Ponticelli, Mary E. Lucas, Lariah Thompson, Christopher DeHaven, Gary Thomas, Angela M. Gronenborn   +7 more
wiley   +1 more source

Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure. [PDF]

Sci Rep
Wang Y, Cheng Y, Sun H, Wang Z, Chen N, Shi C, Liu H, Yang J, Xu Y.   +8 more
europepmc   +1 more source

Isolation and characterization of a functionally active protein translocation apparatus from chloroplasts envelopes [PDF]

, 1993
Morré, D. James, Soll, Jürgen, Waegemann, Karin   +2 more
core  

On the idiosome, golgi apparatus, and acrosome in the male germ cells

, 1922
R. H. Bowen
semanticscholar   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Identification of Molecular Subtypes and Prognostic Features for Triple-Negative Breast Cancer Based on Golgi Apparatus-Related Gene Signature. [PDF]

Oncol Res
Yu Z, Wang J, Xu G.
europepmc   +1 more source

An Arabidopsis reticulon and the atlastin homologue RHD3-like2 act together in shaping the tubular endoplasmic reticulum [PDF]

, 2012
Avisar, Bian, Boevink, Brandizzi, Bubeck, Chen, Chen, Chris Hawes, Cola, DaSilva, Denecke, Hannah Lee, Hellens, Hu, Hu, Hu, Imogen Sparkes, Irons, Karimi, Knop, Kunkel, Lerich, Lilley, Lorenzo Frigerio, Lynne M. Roberts, Moss, Natasha Dzimitrowicz, Nziengui, Oda, Oertle, Orso, Pendin, Runions, Sparkes, Sparkes, Sparkes, Sparkes, Sparkes, Stefano, Stefano Gattolin, Tolley, Tolley, Voeltz, Wang, Zheng   +44 more
core   +1 more source

Mutations in BCAP31 cause a severe X-linked phenotype with deafness, dystonia, and central hypomyelination and disorganize the Golgi apparatus.

American Journal of Human Genetics, 2013
Pierre Cacciagli, Julie Sutera-Sardo, Ana Borges-Correia, J. Roux, I. Dorboz, J. Desvignes, C. Badens, M. Delepine, M. Lathrop, P. Cau, N. Lévy, N. Girard, P. Sarda, O. Boespflug-Tanguy, L. Villard   +14 more
semanticscholar   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

rTMS ameliorates cerebral ischemia-reperfusion injury by inhibiting Golgi apparatus stress through epigenetic modulation of Gli2. [PDF]

Commun Biol
Zhu C, Fan Y, Peng W.
europepmc   +1 more source