Results 261 to 270 of about 1,085,148 (332)

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner, Fabio Frangiamore, Frédéric Sonak, Josef Madl, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +6 more
wiley   +1 more source

GCC2 promotes non-small cell lung cancer progression by maintaining Golgi apparatus integrity and stimulating EGFR signaling pathways. [PDF]

Sci Rep
Kim MS, Jeong H, Choi BH, Park J, Shin GS, Jung JH, Shin H, Kang KW, Jeon OH, Yu J, Park JH, Park Y, Choi Y, Kim HK, Hong S.   +14 more
europepmc   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Function of CSNK2/CK2 selectively affects the endoplasmic reticulum and the Golgi apparatus in mtor-mediated autophagy induction. [PDF]

Autophagy
Sanz-Martinez P, Berkane R, Stolz A.
europepmc   +1 more source

Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells [PDF]

, 2008
Delputte, Peter, Misinzo, Gerald, Nauwynck, Hans   +2 more
core  

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis. [PDF]

Plant Physiol
Kanamori K, Nishimura K, Horie T, Sato MH, Kajino T, Koyama T, Ariga H, Tanaka K, Yotsui I, Sakata Y, Taji T.   +10 more
europepmc   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Spatiotemporal dissection of the Golgi apparatus and the ER-Golgi intermediate compartment in budding yeast. [PDF]

Elife
Tojima T, Suda Y, Jin N, Kurokawa K, Nakano A.   +4 more
europepmc   +1 more source