Results 261 to 270 of about 1,374,879 (330)

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang, Di Gong, Junhong Guo, Wei Huang, Tingyu Hu, Shengbin Tang, Li Li, Bingkai Feng, Kuanrong Dang, Simin Deng, Yong Liu, Chunyan Tan, Fei Yao, Jiantao Wang   +13 more
wiley   +1 more source

Prognosis and metabolism with a Golgi apparatus-related genes-based formula in breast cancer. [PDF]

Medicine (Baltimore)
Lu H, Yu X, Li W, Zhang Y, Sun S.
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Subcellular Fractionation Enables Assessment of Nucleotide Sugar Donors Inside the Golgi Apparatus as a Prerequisite for Unraveling Culture Impacts on Glycoforms of Antibodies. [PDF]

Biotechnol J
Regett N, Dieterle M, Peters F, Deuring M, Stegmaier K, Teleki A, Takors R.   +6 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Tailoring Tumor Cell Golgi Apparatus-Targeting Self-Assembled Peptide for Effective Immunotherapy via Reshaping MIF-Mediated Immunosuppressive Network. [PDF]

Adv Sci (Weinh)
Li X, Wang C, Liu J, Deng G, Deng Y, Hu F, Wang Y, Zhou D.   +7 more
europepmc   +1 more source

H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. [PDF]

PLoS Pathog
Yin Y, Kan X, Miao X, Sun Y, Chen S, Qin T, Ding C, Peng D, Liu X.   +8 more
europepmc   +1 more source

SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus. [PDF]

Cell Mol Life Sci
Song CC, Liu T, Hogstrand C, Zhong CC, Zheng H, Sun LH, Luo Z.   +6 more
europepmc   +1 more source

Optical Nanoscopy of Cytokine-Induced Structural Alterations of the Endoplasmic Reticulum and Golgi Apparatus in Insulin-Secreting Cells. [PDF]

Int J Mol Sci
Pugliese LA, De Lorenzi V, Tesi M, Marchetti P, Cardarelli F.   +4 more
europepmc   +1 more source