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SF1 in the Development of the Adrenal Gland and Gonads

Hormone Research in Paediatrics, 2003
SF1 (steroidogenic factor-1; NR5A1) is an orphan nuclear receptor that is expressed in the adrenal gland, gonads, spleen, ventromedial hypothalamus and pituitary gonadotroph cells. Combined approaches of targeted mutagenesis in mice and examination of the effects of naturally occurring mutations in humans have clarified the role of SF1 in ...
Gokhan, Ozisik   +3 more
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NCAM in developing mouse gonads and ducts

Anatomy and Embryology, 1991
The expression of the Neural Cell Adhesion Molecule, NCAM, in mouse gonads and ducts was studied from fetal life to maturity. The methods used were immunocytochemical staining and Western blotting. The immunocytochemical studies showed that the only structures that remain NCAM-positive throughout life were the mesonephric-derived rete ovarii and rete ...
Møller, Claus J.   +4 more
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The Curious World of Gonadal Development in Mammals

2016
The distinct sex phenotypes of male and female hinge on the development of the fetal gonads as testes or ovaries, in turn, regulated by the molecular genetic machinery of sex determination. Here, I discuss five aspects of mammalian gonadal development that distinguish it from other examples of organogenesis, and continue to surprise and fascinate.
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Development of the gonads in the female japanese quail

American Journal of Anatomy, 1968
AbstractThe germ cells in the Japanese quail, appear in the gonadal area between two to two and one half days incubation with a preferential distribution favoring the left gonad. Proliferation of the primary or medullary cords from the germinal epithelium was observed between four and five and one half days.
J V, Kannankeril, L V, Domm
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Development of sexual dimorphism in the embryonic gonad

Human Genetics, 1981
Differentiation of gonads in embryonic pigs (ages 24 to 44 days) was studied by light and electron microscopy. Incipient short cord-like structures were seen in embryos of both sexes at the age of 24 days. The cords were ultrastructurally similar. Medullary cords appeared in the testis at 26 days and in the ovary at 28 days.
L J, Pelliniemi, L, Lauteala
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Control of Gonadal Development

2012
Preface: Jimenez, R. How to Make a Gonad: Cellular Mechanisms Governing Formation of the Testes and Ovaries: Ungewitter, E.K. Yao, H.H.-C. Genetic Control of Testis Development: Sekido, R. Lovell-Badge, R. Genetic Control of Ovarian Development: Tevosian, S.G. Precious Cargo: Regulation of Sex-Specific Germ Cell Development in Mice: Bowles, J. Koopman,
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Human and mouse gonadal development

Differentiation, 2023
Gerald R. Cunha, Laurence S. Baskin
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Mammalian Sex Determination and Gonad Development

2013
From a developmental biology perspective, gonadogenesis is of particular interest because it provides a unique example of how distinct organs, the testis and ovary, can arise from a common bipotential primordium. Gonadogenesis is also highly relevant from a clinical perspective, as congenital disorders of sex development (DSDs) are not uncommon ...
Wilhelm, D., Yang, J., Thomas, P.
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Plasticity of gonadal development and protandry in fishes

Journal of Experimental Zoology, 1992
AbstractSexual differentiation in eutherian mammals follows a simple governing paradigm: development proceeds in a female direction unless a masculinizing mechanism intervenes. Sexual development in fishes is much more plastic than in mammals. It permits the intervention of environmental factors and follows several different types of sequences that ...
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