Results 41 to 50 of about 215,071 (215)

Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature

BMC Endocrine Disorders, 2023
Background The pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of hypothalamic–pituitary–gonadal axis.
Han Chen, Cai-Yan Mo, Li-yong Zhong
doaj   +1 more source

Early preclinical work with gonadotropin-releasing hormone analogues

F&S Reports, 2023
In this article, I provide a narrative remembrance of the many early proof-of-concept studies that were performed at the Jones Institute for Reproductive Medicine in the late 1980s and early 1990s. A group, led by the late Dr.
Keith Gordon, Ph.D.
doaj   +1 more source

Efficacy of triptorelin pamoate 11.25 mg administered subcutaneously for achieving medical castration levels of testosterone in patients with locally advanced or metastatic prostate cancer

Therapeutic Advances in Urology, 2015
Objectives: Gonadotropin-releasing hormone agonists are widely used as androgen deprivation therapy in many men with locally advanced or metastatic prostate cancer. Gonadotropin-releasing hormone agonists are delivered by intramuscular injection every 1,
Thiery Lebret, Mathieu Rouanne, Oleg Hublarov, Viorel Jinga, Lidiya Petkova, Rumen Kotsev, Ioanel Sinescu, Pascale Dutailly   +7 more
doaj   +1 more source

Investigation the polymorphism of gonadotropin releasing hormone receptor gene in Iraq sheep

The Iraqi Journal of Veterinary Medicine, 2017
In the present study, the investigation includes the estrus activity after synchronization of estrus by using 20 mg impregnated sponges with Medroxy Progesterone Acetate for 12 days with 400 IU I/M injection of pregnant mare serum gonadotropin 24 hrs ...
Hayder Abdul-Kareem Hasan AL-Mutar
doaj   +1 more source

The role of GnRH metabolite, GnRH-(1-5), in endometrial cancer

Frontiers in Endocrinology, 2023
From the time of its discovery and isolation in the mammalian hypothalamus, the decapeptide, gonadotropin-releasing hormone (GnRH), has also been found to be expressed in non-hypothalamic tissues and can elicit a diverse array of functions both in the ...
Madelaine J. Cho-Clark, Allison Watkins, T. John Wu   +2 more
doaj   +1 more source

First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor

BMC Research Notes, 2018
Objectives In vivo evaluations of a gonadotropin releasing hormone-receptor single photon emission computed tomography radiotracer for non-invasive detection of gonadotropin releasing homone-receptors in brain.
Richard Fjellaksel, Ana Oteiza, Montserrat Martin-Armas, Patrick J. Riss, Ole Kristian Hjelstuen, Samuel Kuttner, Jørn H. Hansen, Rune Sundset   +7 more
doaj   +1 more source

Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

eLife, 2021
Gonadotropin-releasing hormone (GnRH) is the primary neuropeptide controlling reproduction in vertebrates. GnRH stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) synthesis via a G-protein-coupled receptor, GnRHR, in the pituitary
Chirine Toufaily, Jérôme Fortin, Carlos AI Alonso, Evelyne Lapointe, Xiang Zhou, Yorgui Santiago-Andres, Yeu-Farn Lin, Yiming Cui, Ying Wang, Dominic Devost, Ferdinand Roelfsema, Frederik Steyn, Aylin C Hanyaloglu, Terence E Hébert, Tatiana Fiordelisio, Derek Boerboom, Daniel J Bernard   +16 more
doaj   +1 more source

Gonadotropin-releasing hormone analogs: Understanding advantages and limitations

Journal of Human Reproductive Sciences, 2014
Pituitary stimulation with pulsatile gonadotropin-releasing hormone (GnRH) analogs induces both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Pratap Kumar, A. Sharma
semanticscholar   +1 more source

Final oocyte maturation with a dual trigger compared to human chorionic gonadotropin trigger in antagonist co-treated cycles: A randomized clinical trial

Middle East Fertility Society Journal, 2018
Objective: This clinical trial compared the effect of a dual trigger treatment (combination of gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG) and hCG alone on oocyte quality and metaphase II oocytes’ number. Methods:
Ashraf Alleyassin, Marzieh Ghasemi, Marzieh Aghahosseini, Leila Safdarian, Fatemeh Sarvi, Amir Almasi-Hashiani, Sedigheh Hosseinimousa, Aida Najafian, Arezoo Esmailzadeh   +8 more
doaj   +1 more source

Development of Gonadotropin-Releasing Hormone Secretion and Pituitary Response

Journal of Neuroscience, 2014
Acquisition of a mature pattern of gonadotropin-releasing hormone (GnRH) secretion from the CNS is a hallmark of the pubertal process. Little is known about GnRH release during sexual maturation, but it is assumed to be minimal before later stages of ...
Katarzyna M Glanowska, L. L. Burger, S. Moenter   +2 more
semanticscholar   +1 more source