Results 51 to 60 of about 215,071 (215)

Regulation of Gonadotropin-Releasing Hormone-(1–5) Signaling Genes by Estradiol Is Age Dependent

Frontiers in Endocrinology, 2017
Gonadotropin-releasing hormone (GnRH) is a key regulatory molecule of the hypothalamus–pituitary (PIT)–gonadal (HPG) axis that ultimately leads to the downstream release of estradiol (E2) and progesterone (P).
Bradly M. Bauman, Weiling Yin, Andrea C. Gore, T. John Wu   +3 more
doaj   +1 more source

Successful outcome of a pregnancy derived from premature ovulation in a gonadotropin‐releasing hormone antagonist protocol: A case report

Clinical Case Reports, 2021
In the gonadotropin‐releasing hormone (GnRH) antagonist protocol, it is necessary to reinforce contraceptive guidance assuming that luteinizing hormone surge is not detected by measurement of serum level and ovulation is not suppressed by GnRH antagonist.
Daichi Inoue, Yoshimasa Asada, Tomoko Ando   +2 more
doaj   +1 more source

Intrinsic and Regulated Gonadotropin-Releasing Hormone Receptor Gene Transcription in Mammalian Pituitary Gonadotrophs

Frontiers in Endocrinology, 2017
The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH), acting via its receptors (GnRHRs) expressed in pituitary gonadotrophs, represents a critical molecule in control of reproductive functions in all vertebrate species.
Marija M. Janjic, Stanko S. Stojilkovic, Ivana Bjelobaba   +2 more
doaj   +1 more source

Applicability of a novel mathematical model for the prediction of adult height and age at menarche in girls with idiopathic central precocious puberty

Clinics, 2018
OBJECTIVES: Unfavorable predicted adult height and psychosocial inadequacy represent parameters used to guide therapeutic intervention in girls with central precocious puberty. Gonadotropin-releasing hormone analog is the first-line treatment. The aim of
Mateus Cavarzan Lopes, Carolina Oliveira Ramos, Ana Claudia Latronico, Berenice B. Mendonça, Vinicius N. Brito   +4 more
doaj   +1 more source

A change from gonadotropin releasing hormone antagonist to gonadotropin releasing hormone agonist therapy does not affect the oncological outcomes in hormone sensitive prostate cancer

Basic and Clinical Andrology, 2018
Résumé Contexte L’objectif de notre étude rétrospective était d’évaluer la survie à 5 ans et le délai de transition du cancer de la prostate hormono-sensible au cancer de la prostate résistant à la castration chez des patients porteurs d’un cancer de la ...
Jumpei Asakawa, Taro Iguchi, Satoshi Tamada, Sayaka Yasuda, Noriko Ninomiya, Minoru Kato, Takeshi Yamasaki, Tetusji Ohmachi, Tatsuya Nakatani   +8 more
doaj   +1 more source

Different clinical courses of central precocious girls according to their age at presentation and treatment [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2013
PurposeThe progressivity of central precocious puberty (CPP) seems to depend on the age at presentation. We evaluated the clinical courses of CPP girls according to their age at initiation of treatment.MethodsOne hundred thirty five girls with CPP ...
Shin-Ae Yoon, Heon-Seok Han, Heon Kim, Sung-Cheol Yun   +3 more
doaj   +1 more source

Molecular Mechanisms of Gonadotropin-Releasing Hormone Signaling: Integrating Cyclic Nucleotides into the Network

Frontiers in Endocrinology, 2013
Gonadotropin-releasing hormone (GnRH) is the primary regulator of mammalian reproductive function in both males and females. It acts via G-protein coupled receptors on gonadotropes to stimulate synthesis and secretion of the gonadotropin hormones ...
R. M. Perrett, C. McArdle
semanticscholar   +1 more source

Gonadotropin-releasing hormone agonist-induced pituitary apoplexy

Endocrinology, Diabetes & Metabolism Case Reports, 2016
Pituitary apoplexy represents an uncommon endocrine emergency with potentially life-threatening consequences. Drug-induced pituitary apoplexy is a rare but important consideration when evaluating patients with this presentation.
Fergus Keane, Aoife M Egan, Patrick Navin, Francesca Brett, Michael C Dennedy   +4 more
doaj   +1 more source

Neuroestradiol in the Hypothalamus Contributes to the Regulation of Gonadotropin Releasing Hormone Release

Journal of Neuroscience, 2013
Release of gonadotropin releasing hormone (GnRH) from the medial basal hypothalamus (MBH)/median eminence region (S-ME) is essential for normal reproductive function.
B. Kenealy, A. Kapoor, Kathryn A. Guerriero, K. Keen, James P. Garcia, Joseph R. Kurian, T. Ziegler, E. Terasawa   +7 more
semanticscholar   +1 more source

Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty

Journal of Neuroscience, 2005
We examined the role of kisspeptin and its receptor, the G-protein-coupled receptor GPR54, in governing the onset of puberty in the mouse. In the adult male and female mouse, kisspeptin (10–100 nm) evoked a remarkably potent, long-lasting depolarization ...
S. Han, M. L. Gottsch, Kathy J Lee, S. Popa, Jeremy T. Smith, Sonya K. Jakawich, D. Clifton, R. Steiner, A. Herbison   +8 more
semanticscholar   +1 more source