Results 61 to 70 of about 74,557 (274)

Regulation of Gonadotropin-Releasing Hormone-(1–5) Signaling Genes by Estradiol Is Age Dependent

Frontiers in Endocrinology, 2017
Gonadotropin-releasing hormone (GnRH) is a key regulatory molecule of the hypothalamus–pituitary (PIT)–gonadal (HPG) axis that ultimately leads to the downstream release of estradiol (E2) and progesterone (P).
Bradly M. Bauman, Weiling Yin, Andrea C. Gore, T. John Wu   +3 more
doaj   +1 more source

Successful outcome of a pregnancy derived from premature ovulation in a gonadotropin‐releasing hormone antagonist protocol: A case report

Clinical Case Reports, 2021
In the gonadotropin‐releasing hormone (GnRH) antagonist protocol, it is necessary to reinforce contraceptive guidance assuming that luteinizing hormone surge is not detected by measurement of serum level and ovulation is not suppressed by GnRH antagonist.
Daichi Inoue, Yoshimasa Asada, Tomoko Ando   +2 more
doaj   +1 more source

Dienogest use and the risk of breast and gynecologic cancers: A nationwide population‐based study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Hoyol Jhang, Saerom Kim, Hyun‐Tae Park, Ju‐Young Shin, Seung‐Ah Choe   +4 more
wiley   +1 more source

Intrinsic and Regulated Gonadotropin-Releasing Hormone Receptor Gene Transcription in Mammalian Pituitary Gonadotrophs

Frontiers in Endocrinology, 2017
The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH), acting via its receptors (GnRHRs) expressed in pituitary gonadotrophs, represents a critical molecule in control of reproductive functions in all vertebrate species.
Marija M. Janjic, Stanko S. Stojilkovic, Ivana Bjelobaba   +2 more
doaj   +1 more source

Medical treatment of fibroids: FIGO best practice guidance

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Even though uterine fibroids are a widespread condition, the range of approved medical treatment options remains limited. In fact, only a few drugs are officially approved for the therapy of fibroids. In both the USA and the European Medicines Agency region, selected gonadotropin‐releasing hormone (GnRH) antagonists have been approved for this
Ivonne Diaz, Mary Ann Lumsden, Magdalena Zeppernick   +2 more
wiley   +1 more source

Applicability of a novel mathematical model for the prediction of adult height and age at menarche in girls with idiopathic central precocious puberty

Clinics, 2018
OBJECTIVES: Unfavorable predicted adult height and psychosocial inadequacy represent parameters used to guide therapeutic intervention in girls with central precocious puberty. Gonadotropin-releasing hormone analog is the first-line treatment. The aim of
Mateus Cavarzan Lopes, Carolina Oliveira Ramos, Ana Claudia Latronico, Berenice B. Mendonça, Vinicius N. Brito   +4 more
doaj   +1 more source

The epidemiology and pathogenesis of uterine fibroids

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Uterine fibroids, or leiomyomas, are the most common benign tumors of the female reproductive tract, ultimately affecting a majority of women worldwide, primarily during their reproductive years. While their origin appears genetic, manifesting in monoclonal tumors, diverse features and mechanisms contribute to their growth and further ...
Malcolm G. Munro, Svetlana N. Tchaikovski, Ally Murji   +2 more
wiley   +1 more source

Syndrome of the Month: Bosma Arhinia Microphthalmia Syndrome

American Journal of Medical Genetics Part A, EarlyView.
Katherine J. K. Patterson, John M. Graham Jr, Natalie D. Shaw   +2 more
wiley   +1 more source

Gynecologic surgery for benign disease: Preserving reproductive potential

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preserving fertility is essential when managing benign gynecologic disorders in reproductive‐aged women. Surgical interventions can impact future fertility, therefore requiring an evidence‐based, individualized approach. The FIGO Committee on Reproductive Endocrinology and Infertility reviewed current literature to develop recommendations for ...
Togas Tulandi, Edgar Mocanu, Nikhil Purandare, Scott M. Nelson, Eytan R. Barnea, Ruth Dolmo Carluccio, Elif Goknur Topcu, Dov Feldberg, FIGO Committee on Reproductive Endocrinology and Infertility, Nikhil Purandare, M. Louise Hull, Ajey Bhardwaj, Andres Calle, Dov Feldberg, Edgar Mocanu, Eytan Barnea, Goknur Topcu, Hrishikesh Pai, Henry Laurie, Ivonne Jeannette Diaz Yamal, Jaideep Malhotra, Gitau Mburu, Scott Nelson, Togas Tulandi   +23 more
wiley   +1 more source

A change from gonadotropin releasing hormone antagonist to gonadotropin releasing hormone agonist therapy does not affect the oncological outcomes in hormone sensitive prostate cancer

Basic and Clinical Andrology, 2018
Résumé Contexte L’objectif de notre étude rétrospective était d’évaluer la survie à 5 ans et le délai de transition du cancer de la prostate hormono-sensible au cancer de la prostate résistant à la castration chez des patients porteurs d’un cancer de la ...
Jumpei Asakawa, Taro Iguchi, Satoshi Tamada, Sayaka Yasuda, Noriko Ninomiya, Minoru Kato, Takeshi Yamasaki, Tetusji Ohmachi, Tatsuya Nakatani   +8 more
doaj   +1 more source