Results 131 to 140 of about 20,360 (146)

The Use of miRNA Panel as a Growth Plate Marker of Short‐Term Response to GH

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Recombinant human growth hormone (GH) therapy shows variable growth responses in patients with growth hormone deficiency (GHD), highlighting the need for reliable biomarkers to predict individual sensitivity. Objective This study investigated circulating microRNAs (miRNAs) involved in growth plate regulation during GH therapy in ...
Caroline Rosa Pellicciari, Thayna Rosa Bispo, Itatiana Ferreira Rodart, Leandra Steinmetz, Adriana Aparecida Siviero Miachon, Angela Maria Spinola e Castro, Durval Damiani, Cristiane Kochi, Carlos Alberto Longui   +8 more
wiley   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak, Karolina Kowalcze, Marek Krzystanek, Witold Szkróbka, Bogusław Okopień   +4 more
wiley   +1 more source

Ramadan Fasting Improves Health‐Related Quality of Life in Patients With Secondary Adrenal Insufficiency: A Prospective Interventional Case‐Control Study

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Intermittent fasting (IF) exposes patients with adrenal insufficiency (AI) to complications related to undertreatment. We aimed to determine the effect of IF during Ramadan on the quality of life of patients with secondary adrenal insufficiency (SAI) compared to healthy controls.
Mariam Mabrouk, Melika Chihaoui, Jameleddine Sta, Chayma Belhadj Slimane, Ibtissem Oueslati, Meriem Yazidi, Fatma Chaker   +6 more
wiley   +1 more source

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

Cell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi, Hengjie Wang, Shuai Zhu, Minjian Chen, Xuejiang Guo, Qiang Wang, Ling Gu   +6 more
wiley   +1 more source

Response to “Gonadotropin Treatment of Cryptorchidism in Congenital Hypogonadotropic Hypogonadism—Age Is No Limit?”

Clinical Endocrinology, Volume 102, Issue 6, Page 706-707, June 2025.
Yoon Hi Cho, Aniruddh Deshpande, Catherine Langusch, Geoffrey Ambler   +3 more
wiley   +1 more source

Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence

Cell Proliferation, EarlyView.
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin, Yaozong Wei, Ao Ning, Wenqi Hu, Pengcheng Wan, Beijia Cao, Bo Pan, Tianyi Lv, Kunlin Du, Xueling Yao, Shuqi Zou, Xiangyi Chen, Shengqin Zang, Jiangfeng Ye, Guozhi Yu, Qiuxia Liang, Liuhong Shen, Lin Zhang, Xiang Chen, Keren Cheng, Li Meng, Guangbin Zhou   +21 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

High Prevalence of Platelet Function Disorders in Women Referred for Surgical Management of Refractory Heavy Menstrual Bleeding

Haemophilia, EarlyView.
ABSTRACT Introduction Heavy menstrual bleeding (HMB) is a common presenting symptom in women with bleeding disorders, yet haemostatic testing is sometimes overlooked, even when refractory HMB requires surgical intervention. Aim To determine the prevalence of bleeding disorders in women referred for surgical management of HMB and investigate screening ...
Alison Delaney, Evangelos I. Kritsotakis, Kevin Horner, Steve Kitchen, Jennifer Sedcole, Ted Baxter, Rhona M. Maclean, Michael Makris, Clare V. Samuelson   +8 more
wiley   +1 more source

Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia

Haemophilia, EarlyView.
ABSTRACT Introduction Glanzmann's thrombasthenia (GT) is an inherited platelet function disorder that may manifest with significant bleeding symptoms; in women and girls (W&Gs), heavy menstrual bleeding (HMB) is very common. GT in pregnancy is associated with an increased risk of postpartum haemorrhage (PPH).
Deborah Obeng‐Tuudah, Ahmad Tarawah, Melike Ozkan, Rezan Abdul‐Kadir   +3 more
wiley   +1 more source

Hair loss in athletic testosterone use in males: a narrative review

International Journal of Dermatology, Volume 64, Issue 4, Page 654-658, April 2025.
Abstract Performance‐enhancing drugs, such as testosterone, are used by athletes and youth to increase muscle growth and strength, particularly among males. However, these therapies potentially pose health risks, including liver toxicity, gynecomastia, and hair loss.
Weeratian Tawanwongsri, Deesha D. Desai, Ambika Nohria, Jerry Shapiro, Kristen I. Lo Sicco   +4 more
wiley   +1 more source